SCHEMBL9329349

SCHEMBL9329349

C=CC(C)=CCC(=C)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.43
HSD17B10 Q99714 1/20 0.43
ALDH1A1 P00352 4/20 0.36
TET2 Q6N021 4/20 0.33
TSHR P16473 4/20 0.32
TP53 P04637 1/20 0.32
LMNA P02545 1/20 0.32
TET3 O43151 1/20 0.31
TET1 Q8NFU7 1/20 0.31
GRIK1 P39086 1/20 0.30
GRIK2 Q13002 1/20 0.30
GRM1 Q13255 1/20 0.30
GRM2 Q14416 1/20 0.30
MAPK1 P28482 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11025461 0.79
SCHEMBL11025463 0.79
SCHEMBL1425600 0.79 ALOX15 (0.38) ALOX15HSD17B10TET2TSHRTET3
SCHEMBL15017599 0.77 ALOX15 (0.37) ALOX15HSD17B10TET2TET3TET1
SCHEMBL212197 0.77 ALOX15 (0.37) ALOX15HSD17B10TET2TET3TET1
Methacrylic Acid SCHEMBL9931511 0.74 ALOX15 (0.34) ALOX15HSD17B10TET2TET3TET1
SCHEMBL27352205 0.74
SCHEMBL4758058 0.74 ALOX15 (0.41) ALOX15HSD17B10ALDH1A1TET2TET3
Methacrylic Acid SCHEMBL4557384 0.73 ALOX15 (0.41) ALOX15HSD17B10ALDH1A1TET2TET3
SCHEMBL1219418 0.72 ALOX15 (0.33) ALOX15HSD17B10TET2TET3TET1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0394377-B1 LUBRICATING OIL COMPOSITIONS LUBRIZOL CORP (US) 1994-04-06 EP disclosed
EP-0318511-B1 BORATED AMINE SALTS OF MONOTHIOPHOSPHORIC ACIDS The Lubrizol Corporation (US) 1992-09-23 EP disclosed
EP-0289548-B1 SULFURIZED COMPOSITONS AND LUBRICANTS The Lubrizol Corporation (US) 1992-07-22 EP disclosed
US-4981602-A An oil additive comprising a mixture of amine and maleic acid-modified polyolefin and a metal dihydrocarbyl dithiophosphoric acid; internal combustion engines; aging resistance THE LUBRIZOL CORPORATION (US) 1991-01-01 US disclosed
EP-0232327-B1 SULFURIZED COMPOSITIONS, AND ADDITIVE CONCENTRATES, LUBRICATING COMPOSITIONS,METAL WORKING LUBRICANTS AND ASPHALT COMPOSITIONS CONTAINING SAME The Lubrizol Corporation (US) 1990-10-03 EP disclosed
US-4952328-A FOR INTERNAL COMBUSTION ENGINES THE LUBRIZOL CORPORATION (US) 1990-08-28 US disclosed
US-4941984-A LUBRICATING OIL, DETERGENTS OF MAGNESIUM SALTS, A SUCCINIC ACID ACYLATED POLYAMINE THE LUBRIZOL CORPORATION (US) 1990-07-17 US disclosed
EP-0211066-B1 SULFUR-CONTAINING COMPOSITIONS, AND ADDITIVE CONCENTRATES AND LUBRICATING OILS CONTAINING SAME The Lubrizol Corporation (US) 1990-05-23 EP disclosed
EP-0216909-B1 LUBRICATING OILS COMPRISING BORON- AND SULFUR-CONTAINING COMPOSITIONS, AND THEIR METHOD OF PREPARATION The Lubrizol Corporation (US) 1990-02-28 EP disclosed
EP-0309486-A1 PHOSPHOROUS- AND SULFUR-CONTAINING LUBRICANT AND FUNCTIONAL FLUID COMPOSITIONS The Lubrizol Corporation (US) 1989-04-05 EP disclosed
US-4755311-A Borated amine salt of dihydrocarbyl monothiophosphoric acid THE LUBRIZOL CORPORATION (US) 1988-07-05 US disclosed
WO-1987007638-A2 PHOSPHOROUS- AND SULFUR-CONTAINING LUBRICANT AND FUNCTIONAL FLUID COMPOSITIONS THE LUBRIZOL CORPORATION (US) 1987-12-17 WO disclosed
US-4623473-A SULFURIZED DIELS-ALDER ADDUCTS, METAL DITHIOCARBAMATES THE LUBRIZOL CORPORATION (US) 1986-11-18 US disclosed
US-4612129-A Sulfur-containing compositions, and additive concentrates and lubricating oils containing same THE LUBRIZOL CORPORATION (US) 1986-09-16 US disclosed
US-4582618-A CONTAINING REACTION PRODUCT OF SULFUR AND DIELS-ALDER ADDUCT THE LUBRIZOL CORPORATION (US) 1986-04-15 US disclosed