Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ULK1 | O75385 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9421827 | 0.79 | TSHR (0.41) | CYP2D6LMNATSHRKMT2AGAA | |
| SCHEMBL8849284 | 0.78 | TSHR (0.32) | TSHR | |
| SCHEMBL11171257 | 0.77 | BCHE (0.43) | CYP2D6LMNACYP3A4 | |
| SCHEMBL10971254 | 0.76 | KMT2A (0.32) | CYP2D6KMT2A | |
| SCHEMBL28294628 | 0.74 | KMT2A (0.44) | CYP2D6LMNATSHRKMT2AGAA | |
| SCHEMBL14590854 | 0.72 | TSHR (0.39) | CYP2D6LMNATSHRKMT2ANR1I2 | |
| SCHEMBL224032 | 0.72 | TSHR (0.33) | TSHRKMT2AGAAALDH1A1HTT | |
| SCHEMBL8387770 | 0.72 | DRD2 (0.43) | CYP2D6LMNATSHRKMT2AALDH1A1 | |
| SCHEMBL19937404 | 0.72 | TSHR (0.39) | CYP2D6LMNATSHRKMT2AGAA | |
| SCHEMBL68167 | 0.71 | TSHR (0.31) | TSHRKMT2AGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0344114-B1 | Unsaturated derivatives of 2,2,6,6-tetramethyl piperidine | CIBA GEIGY AG (CH) | 1994-04-06 | — | — | EP | disclosed |
| US-4942238-A | Unsaturated derivatives of 2,2,6,6-tetramethylpiperidine | CIBA-GEIGY CORPORATION (US) | 1990-07-17 | — | — | US | disclosed |