Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.74 |
| ▸ | MAPT | P10636 | 6/20 | 0.74 |
| ▸ | POLB | P06746 | 2/20 | 0.74 |
| ▸ | BLM | P54132 | 1/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.71 |
| ▸ | LMNA | P02545 | 4/20 | 0.71 |
| ▸ | NPC1 | O15118 | 2/20 | 0.71 |
| ▸ | RAB9A | P51151 | 2/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.71 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.71 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.71 |
| ▸ | RELA | Q04206 | 1/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.64 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.64 |
| ▸ | DDX3X | O00571 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9329754 | 0.93 | MEN1 (0.85) | MEN1KMT2AMAPTPOLBBLM | |
| SCHEMBL8710919 | 0.90 | MEN1 (0.80) | MEN1KMT2AMAPTPOLBBLM | |
| SCHEMBL9800017 | 0.87 | GAA (0.77) | MEN1KMT2AMAPTPOLBBLM | |
| SCHEMBL11572673 | 0.87 | MEN1 (0.76) | MEN1KMT2AMAPTPOLBBLM | |
| SCHEMBL6795867 | 0.87 | MEN1 (0.85) | MEN1KMT2AMAPTPOLBBLM | |
| SCHEMBL13698359 | 0.86 | MEN1 (0.91) | MEN1KMT2AMAPTPOLBBLM | |
| SCHEMBL18941246 | 0.86 | NPC1 (0.66) | MEN1KMT2AMAPTPOLBBLM | |
| SCHEMBL8713931 | 0.86 | KMT2A (0.86) | MEN1KMT2AMAPTPOLBBLM | |
| SCHEMBL1336235 | 0.86 | MEN1 (0.74) | MEN1KMT2AMAPTPOLBBLM | |
| SCHEMBL1454159 | 0.86 | MEN1 (0.74) | MEN1KMT2AMAPTPOLBBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8466180-B2 | Insecticidal compounds | SYNGENTA CROP PROTECTION LLC (US) | 2013-06-18 | — | — | US | disclosed |
| US-8466180-B2 | Insecticidal compounds | SYNGENTA CROP PROTECTION LLC (US) | 2013-06-18 | — | — | US | disclosed |
| US-8466180-B2 | Insecticidal compounds | SYNGENTA CROP PROTECTION LLC (US) | 2013-06-18 | — | — | US | disclosed |
| US-20100076078-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CORP PROTECTION, INC. (US) | 2010-03-25 | — | — | US | disclosed |
| US-20100076078-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CORP PROTECTION, INC. (US) | 2010-03-25 | — | — | US | disclosed |
| US-20100076078-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CORP PROTECTION, INC. (US) | 2010-03-25 | — | — | US | disclosed |
| CN-101578260-A | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2009-11-11 | — | — | CN | disclosed |
| EP-2069287-A1 | INSECTICIDAL COMPOUNDS | Syngeta Participations AG (CH) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008031534-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2008-03-20 | — | — | WO | disclosed |
| WO-2008031534-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2008-03-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100076078-A1 | INSECTICIDAL COMPOUNDS | ACHE, CHRM1, CHRM2 | MEN1 1427/4885KMT2A 2280/4885MAPT 3617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.