Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 1/20 | 0.54 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.51 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | F3 | P13726 | 2/20 | 0.50 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.48 |
| ▸ | TYR | P14679 | 1/20 | 0.48 |
| ▸ | JUN | P05412 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9329953 | 1.00 | GUSB (0.54) | GUSBTAS1R3TAS1R1CYP1A2CYP2D6 | |
| SCHEMBL1126747 | 0.85 | HCAR2 (0.54) | GUSBTAS1R3TAS1R1CYP2C9ALDH1A1 | |
| SCHEMBL12924107 | 0.85 | HCAR2 (0.54) | GUSBTAS1R3TAS1R1CYP2C9ALDH1A1 | |
| SCHEMBL1126746 | 0.85 | HCAR2 (0.54) | GUSBTAS1R3TAS1R1CYP2C9ALDH1A1 | |
| SCHEMBL9256644 | 0.83 | GLA (0.53) | GUSBTAS1R3TAS1R1LMNAMAPT | |
| SCHEMBL6836849 | 0.83 | GUSB (0.51) | GUSBTAS1R3TAS1R1MAPTALOX5 | |
| SCHEMBL1384049 | 0.83 | ALOX5 (0.54) | GUSBTAS1R3TAS1R1ALOX5JAK2 | |
| SCHEMBL6836844 | 0.83 | GUSB (0.51) | GUSBTAS1R3TAS1R1MAPTALOX5 | |
| SCHEMBL1478122 | 0.83 | ALOX5 (0.54) | GUSBTAS1R3TAS1R1ALOX5JAK2 | |
| SCHEMBL9256654 | 0.83 | GLA (0.53) | GUSBTAS1R3TAS1R1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5352802-A | Derivatives of 4H-thiopyran-1,1-dioxide | EASTMAN KODAK COMPANY (US) | 1994-10-04 | — | — | US | disclosed |
| US-5300385-A | Low voltage, high speed | EASTMAN KODAK COMPANY (US) | 1994-04-05 | — | — | US | disclosed |