Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 15/20 | 0.52 |
| ▸ | SSTR1 | P30872 | 6/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.37 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.37 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9329945 | 0.82 | SSTR4 (0.57) | SSTR4SSTR1 | |
| SCHEMBL9346132 | 0.79 | SSTR4 (0.43) | SSTR4SSTR1 | |
| SCHEMBL9330440 | 0.78 | EPHX1 (0.44) | SSTR4SSTR1EPHX1POLBGNAI3 | |
| Fumaric Acid SCHEMBL9345641 | 0.76 | SSTR4 (0.54) | SSTR4SSTR1 | |
| SCHEMBL12334726 | 0.76 | EPHX1 (0.52) | SSTR4SSTR1EPHX1POLBGNAI3 | |
| SCHEMBL12308373 | 0.72 | SSTR4 (0.48) | SSTR4SSTR1EPHX1POLBGNAI3 | |
| SCHEMBL6697632 | 0.71 | EPHX1 (0.59) | SSTR4SSTR1EPHX1POLBGNAI3 | |
| SCHEMBL9799570 | 0.71 | SSTR1 (0.37) | SSTR4SSTR1EPHX1POLBGNAI3 | |
| SCHEMBL15447615 | 0.70 | EPHX1 (0.57) | SSTR4SSTR1EPHX1POLBGNAI3 | |
| SCHEMBL2015296 | 0.70 | ALDH1A1 (0.46) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366004-B1 | Cyclic azaaliphatic compounds with a nitroxy group, process for their preparation and pharmaceutical compositions thereof | BOEHRINGER MANNHEIM GMBH (DE) | 1994-03-30 | — | — | EP | disclosed |
| US-5280031-A | Cyclic azaaliphatic compounds with a nitroxy function, processes for the preparation thereof and pharmaceutical compositions containing them | BOEHRINGER MANNHEIM GMBH (DE) | 1994-01-18 | — | — | US | disclosed |
| US-5030641-A | Treatment of angina pectoris, hypotensive agents | BOEHRINGER MANNHEIM GMBH (DE) | 1991-07-09 | — | — | US | disclosed |
| EP-0366004-A1 | Cyclic azaaliphatic compounds with a nitroxy group, process for their preparation and pharmaceutical compositions thereof | Roche Diagnostics GmbH (DE) | 1990-05-02 | — | — | EP | disclosed |