Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18104962 | 0.86 | FFAR1 (0.46) | GRM5FFAR1POLBCYP2C19ERN1 | |
| SCHEMBL20089251 | 0.81 | GRM5 (0.42) | GRM5FFAR1POLBERN1ALDH1A1 | |
| SCHEMBL13879198 | 0.79 | GRM5 (0.44) | GRM5FFAR1POLBCYP1A2CYP3A4 | |
| SCHEMBL1159454 | 0.75 | GRM5 (0.46) | GRM5FFAR1POLBERN1ALDH1A1 | |
| SCHEMBL8022360 | 0.75 | FFAR1 (0.44) | GRM5FFAR1POLBERN1ALDH1A1 | |
| SCHEMBL18104850 | 0.74 | GRM5 (0.40) | GRM5FFAR1POLBERN1ALDH1A1 | |
| SCHEMBL3946468 | 0.73 | FFAR1 (0.49) | GRM5FFAR1POLBCYP2C19ERN1 | |
| SCHEMBL7590817 | 0.73 | NPSR1 (0.50) | FFAR1POLBALDH1A1NPC1RAB9A | |
| SCHEMBL28502889 | 0.71 | FFAR1 (0.44) | GRM5FFAR1POLBCYP1A2CYP3A4 | |
| SCHEMBL7202454 | 0.71 | MAPT (0.46) | POLBALDH1A1NPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5352802-A | Derivatives of 4H-thiopyran-1,1-dioxide | EASTMAN KODAK COMPANY (US) | 1994-10-04 | — | — | US | disclosed |
| US-5300385-A | Low voltage, high speed | EASTMAN KODAK COMPANY (US) | 1994-04-05 | — | — | US | disclosed |