Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18104962 | 0.85 | FFAR1 (0.46) | FFAR1DAOGRM5RAB9ANPC1 | |
| SCHEMBL1159454 | 0.82 | GRM5 (0.46) | FFAR1DAOGRM5RAB9ANPC1 | |
| SCHEMBL8022360 | 0.82 | FFAR1 (0.44) | FFAR1DAOGRM5RAB9ANPC1 | |
| SCHEMBL7202747 | 0.81 | HSP90AA1 (0.49) | FFAR1DAOGRM5RAB9ANPC1 | |
| SCHEMBL28454253 | 0.79 | RAB9A (0.50) | FFAR1DAOGRM5RAB9ANPC1 | |
| SCHEMBL28502889 | 0.77 | FFAR1 (0.44) | FFAR1DAOGRM5RAB9ANPC1 | |
| SCHEMBL20089251 | 0.77 | GRM5 (0.42) | FFAR1DAOGRM5RAB9ANPC1 | |
| SCHEMBL28824697 | 0.77 | FFAR1 (0.48) | FFAR1RAB9ANPC1ALDH1A1LMNA | |
| SCHEMBL2491796 | 0.77 | GRM5 (0.55) | FFAR1DAOGRM5RAB9ANPC1 | |
| SCHEMBL7205479 | 0.76 | VCP (0.44) | FFAR1RAB9ANPC1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100345827-C | Bicyclic aromatic compound | CT INTERNAT DE RSEARCHES DERMA (FR) | 2007-10-31 | — | — | CN | claimed |
| CN-1443756-A | Bicyclic aromatic compound | CT INTERNAT DE RSEARCHES DERMA (FR) | 2003-09-24 | — | — | CN | claimed |
| CN-1190394-A | bicyclic aromatic compound | CIRD GALDERMA (FR) | 1998-08-12 | — | — | CN | claimed |
| CN-116675599-A | Novel method for synthesizing phenylpropionic acid | 大连理工大学 | 2023-09-01 | — | — | CN | disclosed |
| CN-108404983-B | Preparation and application of ordered mesoporous phenolic resin polymer supported silver catalyst | 华东师范大学 | 2020-08-04 | — | — | CN | disclosed |
| CN-106946682-B | A kind of preparation method of propine acid compounds | 大连理工大学 | 2019-09-27 | — | — | CN | disclosed |
| CN-106946682-A | A kind of preparation method of propine acid compounds | 大连理工大学 | 2017-07-14 | — | — | CN | disclosed |
| CN-105481806-A | Synthetic method and application of five-membered ring compound containing sulfone group | UNIV SOUTH CHINA TECH | 2016-04-13 | — | — | CN | disclosed |
| WO-2009023160-A2 | NOVEL INHIBITORS OF BACTERIAL SORTASE ENZYMES AND METHODS OF USING THE SAME | THE UAB RESEARCH FOUNDATION (US) | 2009-02-19 | — | — | WO | disclosed |