Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 9/20 | 0.42 |
| ▸ | ESR1 | P03372 | 8/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1597822 | 0.93 | ESR2 (0.47) | ESR2ESR1TSHRHSD17B10CA2 | |
| SCHEMBL3917934 | 0.88 | ESR2 (0.41) | ESR2ESR1TSHRHSD17B10BACE1 | |
| SCHEMBL30343452 | 0.85 | ESR2 (0.50) | ESR2ESR1TSHRHSD17B10CA2 | |
| SCHEMBL1595522 | 0.85 | ESR2 (0.50) | ESR2ESR1TSHRHSD17B10CA2 | |
| SCHEMBL1596654 | 0.81 | ESR1 (0.46) | ESR2ESR1TSHRHSD17B10CA2 | |
| SCHEMBL5710018 | 0.80 | CA2 (0.40) | ESR2TSHRHSD17B10CA2CA1 | |
| SCHEMBL11013342 | 0.79 | ESR2 (0.44) | ESR2ESR1TSHRHSD17B10CA2 | |
| SCHEMBL30343467 | 0.77 | ESR2 (0.50) | ESR2ESR1TSHRHSD17B10CA2 | |
| SCHEMBL1597446 | 0.77 | ESR2 (0.50) | ESR2ESR1TSHRHSD17B10CA2 | |
| SCHEMBL9838263 | 0.77 | ESR1 (0.46) | ESR2ESR1TSHRHSD17B10CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0304125-B1 | Heat-hardenable compositions based on polyglycidyl ethers and polyhydric phenols, halogenated tetraphenols, polyglycidyl ethers and process for preparing tetraphenols | SHELL INT RESEARCH (NL) | 1994-03-23 | — | — | EP | disclosed |
| EP-0304125-A2 | Heat-hardenable compositions based on polyglycidyl ethers and polyhydric phenols, halogenated tetraphenols, polyglycidyl ethers and process for preparing tetraphenols | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1989-02-22 | — | — | EP | disclosed |