Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9330196 | 1.00 | SLC6A4 (0.45) | SLC6A4PSMB5ALDH1A1MEN1NPC1 | |
| SCHEMBL10586846 | 0.80 | SLC6A4 (0.37) | SLC6A4PSMB5ALDH1A1NPC1RAB9A | |
| SCHEMBL10586849 | 0.80 | SLC6A4 (0.37) | SLC6A4PSMB5ALDH1A1NPC1RAB9A | |
| SCHEMBL9329013 | 0.77 | SLC6A4 (0.42) | SLC6A4PSMB5ALDH1A1MEN1NPC1 | |
| SCHEMBL9656460 | 0.73 | CHRNB2 (0.41) | SLC6A4PSMB5RAB9AHCRTR1HCRTR2 | |
| SCHEMBL9656452 | 0.73 | CHRNB2 (0.41) | SLC6A4PSMB5RAB9AHCRTR1HCRTR2 | |
| SCHEMBL9328852 | 0.73 | CHRNB2 (0.41) | SLC6A4PSMB5RAB9AHCRTR1HCRTR2 | |
| SCHEMBL9656446 | 0.73 | CHRNB2 (0.41) | SLC6A4PSMB5RAB9AHCRTR1HCRTR2 | |
| SCHEMBL9328846 | 0.73 | CHRNB2 (0.41) | SLC6A4PSMB5RAB9AHCRTR1HCRTR2 | |
| SCHEMBL3088721 | 0.71 | PSMB5 (0.61) | SLC6A4PSMB5ALDH1A1MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0321274-B1 | Derivatives of thioformamide | MAY & BAKER LTD (GB) | 1994-03-30 | — | — | EP | disclosed |