Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | RORC | P51449 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9551016 | 1.00 | MAPT (0.56) | MAPTHSD17B10KMT2AVCAM1CYP1A2 | |
| SCHEMBL9330256 | 0.89 | MAPT (0.51) | MAPTHSD17B10KMT2AVCAM1CYP1A2 | |
| SCHEMBL10853526 | 0.85 | MAPT (0.53) | MAPTHSD17B10KMT2AVCAM1CYP1A2 | |
| SCHEMBL9385208 | 0.85 | MAPT (0.53) | MAPTHSD17B10KMT2AVCAM1CYP1A2 | |
| SCHEMBL9358684 | 0.85 | ERN1 (0.59) | MAPTKMT2AHTTALDH1A1MEN1 | |
| SCHEMBL9358680 | 0.85 | ERN1 (0.59) | MAPTKMT2AHTTALDH1A1MEN1 | |
| SCHEMBL16971054 | 0.85 | ALDH1A1 (0.50) | MAPTKMT2AHTTALDH1A1MEN1 | |
| SCHEMBL9307151 | 0.84 | MAPT (0.52) | MAPTHSD17B10KMT2ACYP1A2CYP2D6 | |
| SCHEMBL9307154 | 0.84 | MAPT (0.52) | MAPTHSD17B10KMT2ACYP1A2CYP2D6 | |
| SCHEMBL9399639 | 0.83 | GLO1 (0.57) | MAPTHSD17B10KMT2AVCAM1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240659-B2 | N-substituted 3,4,5,6-tetrahydrophthalimides and their precursors | BASF AG (DE) | 1994-10-26 | — | — | EP | disclosed |
| US-5237089-A | Herbicides | BASF AKTIENGESELLSCHAFT (DE) | 1993-08-17 | — | — | US | disclosed |
| US-5062884-A | Herbicides | BASF AKTIENGESELLSCHAFT (DE) | 1991-11-05 | — | — | US | disclosed |
| EP-0240659-A2 | N-substituted 3,4,5,6-tetrahydrophthalimides and their precursors | BASF Aktiengesellschaft (DE) | 1987-10-14 | — | — | EP | disclosed |