Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | NT5E | P21589 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10502068 | 0.88 | NT5E (0.51) | MAPTNT5EALDH1A1GAAHTT | |
| SCHEMBL9328501 | 0.83 | MAPT (0.53) | MAPTNT5EALDH1A1GAATHRB | |
| SCHEMBL9327344 | 0.80 | LMNA (0.44) | MAPTALDH1A1GAALMNA | |
| SCHEMBL28419026 | 0.79 | SMN1; SMN2 (0.53) | MAPTNT5EALDH1A1GAAHTT | |
| SCHEMBL1844429 | 0.78 | MAPT (0.54) | MAPTALDH1A1GAATHRBHTT | |
| SCHEMBL13059466 | 0.77 | MAPT (0.49) | MAPTALDH1A1LMNAHCAR3KMT2A | |
| SCHEMBL5982382 | 0.76 | KAT2B (0.64) | MAPTALDH1A1HTTLMNAKMT2A | |
| SCHEMBL18395639 | 0.76 | MAPT (0.56) | MAPTALDH1A1GAATHRBHTT | |
| SCHEMBL6660827 | 0.76 | HPGD (0.41) | MAPTALDH1A1GAAL3MBTL1LMNA | |
| SCHEMBL3824748 | 0.76 | MAPT (0.51) | MAPTALDH1A1GAATHRBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413230-B1 | Nitroaniline sulphonic acids and process for preparing phenylenediamino sulphonic acids | BASF AG (DE) | 1994-03-30 | — | — | EP | disclosed |
| US-5260431-A | Nitroanilinesulfonic acids and the preparation of phenylenediaminesulfonic acids | BASF AKTIENGESELLSCHAFT (DE) | 1993-11-09 | — | — | US | disclosed |
| EP-0413230-A1 | Nitroaniline sulphonic acids and process for preparing phenylenediamino sulphonic acids | BASF Aktiengesellschaft (DE) | 1991-02-20 | — | — | EP | disclosed |