Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 7/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9329927 | 0.79 | ADORA2B (0.36) | MAPK1ALDH1A1POLBSMN1; SMN2CYP19A1 | |
| SCHEMBL9332756 | 0.73 | ALDH1A1 (0.38) | MAPK1ALDH1A1POLBSMN1; SMN2CYP19A1 | |
| SCHEMBL10654864 | 0.72 | GAA (0.47) | LMNA | |
| SCHEMBL7559919 | 0.69 | MAPT (0.53) | MAPK1ALDH1A1POLBSMN1; SMN2CYP19A1 | |
| SCHEMBL9330024 | 0.67 | MAPT (0.37) | MAPK1ALDH1A1POLBSMN1; SMN2LMNA | |
| SCHEMBL11971531 | 0.67 | MAOB (0.47) | MAPK1ALDH1A1POLBSMN1; SMN2CYP19A1 | |
| SCHEMBL10476077 | 0.67 | MAOB (0.47) | MAPK1ALDH1A1POLBSMN1; SMN2CYP19A1 | |
| SCHEMBL24306681 | 0.67 | MAPT (0.42) | MAPK1ALDH1A1POLBSMN1; SMN2LMNA | |
| SCHEMBL7664076 | 0.66 | ADORA2B (0.34) | MAPK1ALDH1A1POLBSMN1; SMN2CYP19A1 | |
| SCHEMBL7664073 | 0.66 | ADORA2B (0.34) | MAPK1ALDH1A1POLBSMN1; SMN2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5352802-A | Derivatives of 4H-thiopyran-1,1-dioxide | EASTMAN KODAK COMPANY (US) | 1994-10-04 | — | — | US | disclosed |
| US-5300385-A | Low voltage, high speed | EASTMAN KODAK COMPANY (US) | 1994-04-05 | — | — | US | disclosed |