Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.74 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.74 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.74 |
| ▸ | ATM | Q13315 | 1/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.73 |
| ▸ | TSHR | P16473 | 3/20 | 0.72 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.72 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.71 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.65 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31302688 | 1.00 | SMN1; SMN2 (0.74) | SMN1; SMN2ACE2NPSR1ATMKDM4E | |
| SCHEMBL4580492 | 0.93 | KDM4E (0.82) | SMN1; SMN2ACE2NPSR1ATMKDM4E | |
| SCHEMBL16392405 | 0.86 | SMN1; SMN2 (0.97) | SMN1; SMN2KDM4ETSHRCYP2C19MAPT | |
| SCHEMBL4579674 | 0.86 | SMN1; SMN2 (0.97) | SMN1; SMN2KDM4ETSHRCYP2C19MAPT | |
| SCHEMBL6697306 | 0.86 | SMN1; SMN2 (0.71) | SMN1; SMN2ACE2NPSR1ATMKDM4E | |
| SCHEMBL24323728 | 0.86 | SMN1; SMN2 (0.71) | SMN1; SMN2ACE2NPSR1ATMKDM4E | |
| SCHEMBL16392457 | 0.86 | SMN1; SMN2 (0.97) | SMN1; SMN2KDM4ETSHRCYP2C19MAPT | |
| SCHEMBL16370963 | 0.86 | SMN1; SMN2 (0.71) | SMN1; SMN2ACE2NPSR1ATMKDM4E | |
| SCHEMBL16371128 | 0.86 | KDM4E (0.77) | SMN1; SMN2NPSR1KDM4ETSHRMAPT | |
| SCHEMBL22875771 | 0.85 | ACE2 (1.00) | SMN1; SMN2ACE2NPSR1ATMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0587823-A1 | USING THE IMMUNOACTIVATING ACTIVITY OF 3-NAPHTHYLOXY-2-HYDROXY-PROPYLAMINES, IN PARTICULAR FOR PROVIDING CELL IMMUNITY, E.G. AGAINST VIRAL INFECTIONS | PEUSCHEL, Karin, Elisabeth (CH) | 1994-03-23 | — | — | EP | disclosed |
| WO-1993013049-A1 | USING THE IMMUNOACTIVATING ACTIVITY OF 3-NAPHTHYLOXY-2-HYDROXY-PROPYLAMINES, IN PARTICULAR FOR PROVIDING CELL IMMUNITY, E.G. AGAINST VIRAL INFECTIONS | PEUSCHEL KARIN ELISABETH (CH) | 1993-07-08 | — | — | WO | disclosed |