SCHEMBL4580492

SCHEMBL4580492

OC(COc1ccc2ccccc2c1)CN1CCN(CC(O)COc2ccc3ccccc3c2)CC1

nearest known ligand 0.89

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.82
SMN1; SMN2 Q16637 3/20 0.80
MAPT P10636 2/20 0.75
POLB P06746 3/20 0.73
L3MBTL1 Q9Y468 1/20 0.68
NPSR1 Q6W5P4 2/20 0.67
HTT P42858 2/20 0.66
UBE2N P61088 1/20 0.66
ACE2 Q9BYF1 1/20 0.62
MAPK1 P28482 2/20 0.62
USP2 O75604 2/20 0.62
HSD17B10 Q99714 1/20 0.62
TSHR P16473 2/20 0.61
GLA P06280 1/20 0.61
ATM Q13315 1/20 0.60
HPGD P15428 1/20 0.60
CYP2D6 P10635 1/20 0.60
HIF1A Q16665 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16371128 0.93 KDM4E (0.77) KDM4ESMN1; SMN2MAPTPOLBL3MBTL1
SCHEMBL31302688 0.93 SMN1; SMN2 (0.74) KDM4ESMN1; SMN2MAPTPOLBNPSR1
SCHEMBL9330581 0.93 SMN1; SMN2 (0.74) KDM4ESMN1; SMN2MAPTPOLBNPSR1
SCHEMBL24355418 0.92 KDM4E (0.97) KDM4ESMN1; SMN2MAPTPOLBL3MBTL1
SCHEMBL4753148 0.91 KDM4E (0.70) KDM4ESMN1; SMN2MAPTPOLBL3MBTL1
SCHEMBL4579674 0.90 SMN1; SMN2 (0.97) KDM4ESMN1; SMN2MAPTPOLBL3MBTL1
SCHEMBL16392405 0.90 SMN1; SMN2 (0.97) KDM4ESMN1; SMN2MAPTPOLBL3MBTL1
SCHEMBL24323728 0.90 SMN1; SMN2 (0.71) KDM4ESMN1; SMN2MAPTPOLBL3MBTL1
SCHEMBL16392457 0.90 SMN1; SMN2 (0.97) KDM4ESMN1; SMN2MAPTPOLBL3MBTL1
SCHEMBL16370963 0.90 SMN1; SMN2 (0.71) KDM4ESMN1; SMN2MAPTPOLBL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11930815-B1 3,3′-(piperazine-1,4-diyl)bis(1-(naphthalen-2-yloxy)propan-2-ol) as insecticidal agent King Faisal University (SA) 2024-03-19 US claimed
US-11930815-B1 3,3′-(piperazine-1,4-diyl)bis(1-(naphthalen-2-yloxy)propan-2-ol) as insecticidal agent King Faisal University (SA) 2024-03-19 US disclosed
US-11930815-B1 3,3′-(piperazine-1,4-diyl)bis(1-(naphthalen-2-yloxy)propan-2-ol) as insecticidal agent King Faisal University (SA) 2024-03-19 US disclosed
US-11930815-B1 3,3′-(piperazine-1,4-diyl)bis(1-(naphthalen-2-yloxy)propan-2-ol) as insecticidal agent King Faisal University (SA) 2024-03-19 US disclosed
EP-1298490-B1 Photopolymerizable composition and recording material FUJIFILM CORP (JP) 2008-08-13 EP disclosed
US-7399569-B2 Method for producing microcapsules, microcapsules, recording material, and heat-sensitive recording material FUJIFILM CORPORATION (JP) 2008-07-15 US disclosed
US-7300738-B2 Azolinyl acetic acid derivative and azolinyl acetic acid derivative containing recording material FUJIFILM CORPORATION (JP) 2007-11-27 US disclosed
US-7220529-B2 Photopolymerizable composition and recording material using the same FUJIFILM CORPORATION (JP) 2007-05-22 US disclosed
US-7205083-B2 Recording material FUJIFILM CORPORATION (JP) 2007-04-17 US disclosed
EP-1254780-B1 Recording material FUJI PHOTO FILM CO LTD (JP) 2007-01-03 EP disclosed
EP-1035124-A1 Borate compound, and photopolymerizable composition and recording material which contain the same FUJI PHOTO FILM CO., LTD. (JP) 2000-09-13 EP disclosed
US-6060206-A Photo- and heat-sensitive recording material and colorant produced from the material FUJI PHOTO FILM CO., LTD. (JP) 2000-05-09 US disclosed
US-6017672-A MIXTURE OF DIAZONIUM SALT HAVING ABSORPTION WAVELENGTH SHORTER THAN 350 NANOMETERS AND A THERMALLY REACTIVE COUPLER CONTAINED WITHIN RECORDING LAYER COATED ONTO SUPPORT; STORAGE STABILITY, PHOTOSTABILITY, HIGH COLOR DENSITY FUJI PHOTO FILM CO., LTD. (JP) 2000-01-25 US disclosed
US-5998082-A DIHYDROCARBYLOXYPHENYL DIAZONIUM COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1999-12-07 US disclosed
EP-0930529-A1 Heat-sensitive recording material Fuji Photo Film., Ltd. (JP) 1999-07-21 EP disclosed
EP-0827020-A1 Thermal recording material FUJI PHOTO FILM CO., LTD. (JP) 1998-03-04 EP disclosed
EP-0809145-A1 Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 1997-11-26 EP disclosed
US-5543260-A RED COLOR; STORAGE STABILITY; COLORFASTNESS FUJI PHOTO FILM CO., LTD. (JP) 1996-08-06 US disclosed
US-5236800-A Support; diazo compound; no solvnet; coupling component; basic substance; shelf life FUJI PHOTO FILM CO., LTD. (JP) 1993-08-17 US disclosed
US-4975353-A Support and layer of diazo compound, coupling component for coloration and basic compound FUJI PHOTO FILM CO., LTD. (JP) 1990-12-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11930815-B1 3,3′-(piperazine-1,4-diyl)bis(1-(naphthalen-2-yloxy)propan-2-ol) as insecticidal agent GAP43, CASP3, CASP2 KDM4E 3300/4885SMN1; SMN2 225/4885MAPT 2807/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.