SCHEMBL6697306

SCHEMBL6697306

OC(COc1ccc2ccccc2c1)CN1CCNCC1

nearest known ligand 0.78

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.71
KDM4E B2RXH2 4/20 0.70
MAPT P10636 2/20 0.64
POLB P06746 4/20 0.63
NPSR1 Q6W5P4 2/20 0.60
HTT P42858 2/20 0.57
UBE2N P61088 1/20 0.57
MAPK1 P28482 2/20 0.56
RAB9A P51151 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
ACE2 Q9BYF1 1/20 0.56
HPGD P15428 1/20 0.54
USP2 O75604 1/20 0.54
HSD17B10 Q99714 1/20 0.54
ATM Q13315 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24323728 1.00 SMN1; SMN2 (0.71) SMN1; SMN2KDM4EMAPTPOLBNPSR1
SCHEMBL4580492 0.90 KDM4E (0.82) SMN1; SMN2KDM4EMAPTPOLBNPSR1
SCHEMBL9330581 0.86 SMN1; SMN2 (0.74) SMN1; SMN2KDM4EMAPTPOLBNPSR1
SCHEMBL31302688 0.86 SMN1; SMN2 (0.74) SMN1; SMN2KDM4EMAPTPOLBNPSR1
SCHEMBL5878421 0.85 L3MBTL1 (0.77) SMN1; SMN2KDM4EPOLBMAPK1RAB9A
SCHEMBL24322808 0.85 L3MBTL1 (0.77) SMN1; SMN2KDM4EPOLBMAPK1RAB9A
SCHEMBL16392457 0.84 SMN1; SMN2 (0.97) SMN1; SMN2KDM4EMAPTPOLBMAPK1
SCHEMBL16370963 0.84 SMN1; SMN2 (0.71) SMN1; SMN2KDM4EMAPTPOLBNPSR1
SCHEMBL4579674 0.84 SMN1; SMN2 (0.97) SMN1; SMN2KDM4EMAPTPOLBMAPK1
SCHEMBL16371128 0.84 KDM4E (0.77) SMN1; SMN2KDM4EMAPTPOLBNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040220054-A1 Recording material FUJI PHOTO FILM CO., LTD. 2004-11-04 US disclosed
US-6787502-B2 INCLUSION OF A STRONGLY BASIC BIS-GUANIDINE COMPOUND THAT IS SUPERIOR IN DIFFUSION RESISTANCE; SPECIFIED DIAZONIUM SALT COMPOUND AND A PYRROLO(1,2-A)PYRIMIDINE COUPLER IN RECORDING LAYER FUJI PHOTO FILM CO., LTD. (JP) 2004-09-07 US disclosed
US-20040048185-A1 Heat-sensitive recording material FUJI PHOTO FILM CO., LTD 2004-03-11 US disclosed
CN-1461705-A Thermosensitive recording material FUJI PHOTO FILM CO LTD (JP) 2003-12-17 CN disclosed
US-20030158038-A1 Guanidine compound and heat sensitive recording material FUJI PHOTO FILM CO., LTD. 2003-08-21 US disclosed
US-6416922-B2 DRY PROCESSING PHOTOGRAPHY FUJI PHOTO FILM CO., LTD. (JP) 2002-07-09 US disclosed
US-20020065194-A1 Guanidine compound and heat sensitive recording material FUJI PHOTO FILM CO., LTD. 2002-05-30 US disclosed
US-6348529-B1 THERMOSENSITIVE RECORDING WITH TWO ETHERS AND TWO GUANIDINE GROUPS FUJI PHOTO FILM CO., LTD. (JP) 2002-02-19 US disclosed
US-5935757-A HIGH COLOR DEVELOPING SENSITIVITY AND EXCELLENT STORABILITY. USING AN ESTER- OR AMIDE CONTAINING SULFOAMIDOBENZENE IN A LAYER CONTAINING A DIAZONIUM SALT AND A REACTIVE COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1999-08-10 US disclosed
US-5925489-A CONTAINING DIAZONIUM SALT AND PYRROLOPYRIMIDINE COUPLER WHICH REACT WHEN HEATED TO DEVELOP VIOLET TO CYAN COLORS, IMAGE QUALITY AND STABILITY, SHELF LIFE FUJI PHOTO FILM CO., LTD. (JP) 1999-07-20 US disclosed
US-5866293-A CONTAINING DIAZO COMPOUND AND PYRAZOLONE COUPLER; STORAGE STABILITY FUJI PHOTO FILM CO., LTD. (JP) 1999-02-02 US disclosed
US-5683850-A HAVING EXCELLENT RAW STOCK STORABILITY AND IMAGE STORAGE CHARACTERISTICS FUJI PHOTO FILM CO., LTD. (JP) 1997-11-04 US disclosed
EP-0327318-B1 Heat-sensitive recording materials FUJI PHOTO FILM CO LTD (JP) 1995-07-19 EP disclosed
EP-0337734-B1 Heat-developable diazo copying material FUJI PHOTO FILM CO LTD (JP) 1995-03-08 EP disclosed
EP-0327318-A2 Heat-sensitive recording materials FUJI PHOTO FILM CO., LTD. (JP) 1989-08-09 EP disclosed