Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPI | P34949 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CD44 | P16070 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SNCA | P37840 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4601919 | 0.79 | GAA (0.34) | MPITDP1KDM4EGAAMEN1 | |
| SCHEMBL14428064 | 0.74 | MPI (0.30) | MPITDP1KDM4EGAANSD2 | |
| Questiomycin B SCHEMBL9330329 | 0.73 | TSHR (0.44) | MPITDP1KDM4EGAAMEN1 | |
| SCHEMBL8397425 | 0.71 | HTT (0.51) | MPITDP1KDM4EGAAMEN1 | |
| SCHEMBL918366 | 0.71 | HTT (0.51) | MPITDP1KDM4EGAAMEN1 | |
| SCHEMBL6859897 | 0.70 | MPI (0.32) | MPITDP1 | |
| SCHEMBL11444474 | 0.70 | NR1H2 (0.36) | GAAMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL6574797 | 0.70 | MAPT (0.42) | TDP1KDM4EGAAMEN1KMT2A | |
| SCHEMBL7712519 | 0.69 | MYC (0.44) | KDM4EGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL5850231 | 0.69 | HTR7 (0.41) | KDM4EMEN1KMT2AHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0339661-B1 | Photochromic substances | RODENSTOCK OPTIK G (DE) | 1994-04-20 | — | — | EP | disclosed |
| EP-0339661-A2 | Photochromic substances | Optische Werke G. Rodenstock (DE) | 1989-11-02 | — | — | EP | disclosed |