SCHEMBL918366

SCHEMBL918366

C=C1N(C)c2ccccc2C1(C)C

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 8/20 0.51
LMNA P02545 7/20 0.51
MAPT P10636 13/20 0.47
KMT2A Q03164 10/20 0.45
MEN1 O00255 9/20 0.45
KDM4E B2RXH2 8/20 0.45
THRB P10828 5/20 0.45
RECQL P46063 5/20 0.45
GAA P10253 5/20 0.45
ALDH1A1 P00352 5/20 0.45
TSHR P16473 2/20 0.45
NPSR1 Q6W5P4 2/20 0.45
POLB P06746 3/20 0.44
CYP2D6 P10635 2/20 0.44
HSD17B10 Q99714 2/20 0.44
NPC1 O15118 1/20 0.44
CYP3A4 P08684 1/20 0.44
APOBEC3A P31941 1/20 0.44
CYP2C19 P33261 1/20 0.44
RAB9A P51151 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8397425 1.00 HTT (0.51) HTTLMNAMAPTKMT2AMEN1
Sulfuric Acid SCHEMBL29018862 0.89 LMNA (0.47) HTTLMNAMAPTKMT2AMEN1
SCHEMBL9550828 0.85 NOTUM (0.45) HTTLMNAMAPTKMT2AMEN1
Questiomycin B SCHEMBL9330329 0.84 TSHR (0.44) HTTLMNAMAPTKMT2AMEN1
SCHEMBL29438184 0.82 HTT (0.58) HTTLMNAMAPTKMT2AMEN1
SCHEMBL280367 0.82 HTT (0.58) HTTLMNAMAPTKMT2AMEN1
SCHEMBL4603835 0.79 KMT2A (0.53) HTTLMNAMAPTKMT2AMEN1
SCHEMBL9736446 0.77 HTT (0.39) HTTLMNAMAPTKMT2AMEN1
SCHEMBL4615970 0.77 HTT (0.39) HTTLMNAMAPTKMT2AMEN1
SCHEMBL5850668 0.77 PGR (0.41) HTTLMNAMAPTKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1185 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115448929-B Preparation method and application of compound 阜阳欣奕华制药科技有限公司 2023-08-11 CN claimed
CN-112174871-B Process for preparing indolines 白银帕潘纳科技有限公司 2021-08-20 CN claimed
CN-109762000-B 1, 8-naphthalimide unit-based spirooxazine hydrogen ion fluorescent probe compound and synthetic method and application thereof 赤峰学院 2021-03-30 CN claimed
CN-109081836-B Mercury ion near-infrared fluorescent probe based on hemicyanine structure and preparation method and application thereof 许昌学院 2021-03-30 CN claimed
CN-109627267-B Iridium complex, and synthesis method and application thereof 南京工业大学 2020-08-28 CN claimed
CN-109053694-B Method for preparing indoline methine dye by one-pot method 宁波龙欣精细化工有限公司 2020-06-26 CN claimed
CN-107299526-B A kind of preparation method of photochromic fabric 东华大学 2019-07-23 CN claimed
CN-109627267-A Iridium complex, and synthesis method and application thereof 南京工业大学 2019-04-16 CN claimed
CN-109266331-A A kind of near infrared fluorescent probe, preparation method and application for surveying hypochlorite ion based on half flower cyanines structure 许昌学院 2019-01-25 CN claimed
CN-109206440-A Spirooxazine class photochromic compound 苏州健雄职业技术学院 2019-01-15 CN claimed
WO-2000038633-A1 AGENT FOR DYING KERATIN FIBERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2000-07-06 WO claimed
WO-2000033799-A1 AGENT FOR COLORING FIBERS WELLA AKTIENGESELLSCHAFT (DE) 2000-06-15 WO claimed
EP-0948570-A1 METHOD FOR PREPARING LIGHT-ABSORBING POLYMERIC COMPOSITIONS EASTMAN CHEMICAL COMPANY (US) 1999-10-13 EP claimed
WO-1998023690-A9 METHOD FOR PREPARING LIGHT-ABSORBING POLYMERIC COMPOSITIONS 1998-09-17 WO claimed
WO-1998023690-A1 METHOD FOR PREPARING LIGHT-ABSORBING POLYMERIC COMPOSITIONS EASTMAN CHEMICAL COMPANY (US) 1998-06-04 WO claimed
EP-0605566-A1 LIGHT-ABSORBING POLYURETHANE COMPOSITIONS AND THERMOPLASTIC POLYMERS COLORED THEREWITH EASTMAN CHEMICAL COMPANY (US) 1994-07-13 EP claimed
EP-0272212-B1 PROCESS FOR CONTINUALLY PRODUCING AZO OR HYDRAZONE DYES CIBA-GEIGY AG (CH) 1993-09-01 EP claimed
WO-1993006147-A1 LIGHT-ABSORBING POLYURETHANE COMPOSITIONS AND THERMOPLASTIC POLYMERS COLORED THEREWITH EASTMAN KODAK COMPANY (US) 1993-04-01 WO claimed
US-5194463-A LIGHT-ABSORBING POLYURETHANE COMPOSITIONS AND THERMOPLASTIC POLYMERS COLORED THEREWITH EASTMAN KODAK COMPANY (US) 1993-03-16 US claimed
US-3950356-A SYNTHESIS OF PHOTOCHROMIC INDOLINESPIROPYRANS SAINT-GOBAIN INDUSTRIES (FR) 1976-04-13 US claimed