Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 5/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL933064 | 0.84 | CYP19A1 (0.43) | CYP19A1CYP3A4CYP2C9CYP2C19MAPT | |
| SCHEMBL9794542 | 0.80 | CYP19A1 (0.48) | CYP19A1CYP3A4CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL933961 | 0.76 | POLB (0.43) | CYP19A1CYP3A4CYP2C9CYP2C19MAPT | |
| SCHEMBL934753 | 0.76 | CYP19A1 (0.41) | CYP19A1CYP3A4CYP2C9CYP2C19MAPT | |
| SCHEMBL9465726 | 0.73 | CYP19A1 (0.40) | CYP19A1CYP3A4CYP2C9CYP2C19MAPT | |
| SCHEMBL3021832 | 0.73 | CYP19A1 (0.55) | CYP19A1CYP3A4CYP2C9CYP2C19CYP3A5 | |
| SCHEMBL9466364 | 0.73 | CYP3A4 (0.38) | CYP19A1CYP3A4CYP2C9CYP2C19MAPT | |
| SCHEMBL9466379 | 0.72 | CYP19A1 (0.39) | CYP19A1CYP3A4CYP2C9CYP2C19MAPT | |
| SCHEMBL12870549 | 0.71 | CYP19A1 (0.41) | CYP19A1CYP3A4CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL10999210 | 0.71 | KCNA5 (0.47) | CYP19A1CYP3A4CYP2C9CYP2C19KCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2451784-A1 | PHENYL(OXY/THIO)ALKANOL DERIVATIVES | Bayer CropScience AG (DE) | 2012-05-16 | — | — | EP | disclosed |
| WO-2011003527-A1 | PHENYL(OXY/THIO)ALKANOL DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2011-01-13 | — | — | WO | disclosed |