Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 5/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10999210 | 0.88 | KCNA5 (0.47) | CYP19A1CYP3A4CYP2C9CYP2C19KCNA5 | |
| SCHEMBL12870549 | 0.85 | CYP19A1 (0.41) | CYP19A1CYP3A4CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL933065 | 0.84 | CYP19A1 (0.43) | CYP19A1CYP3A4CYP2C9CYP2C19MAPT | |
| SCHEMBL9375772 | 0.79 | POLB (0.41) | CYP19A1CYP3A4MAPTKMT2ACYP3A5 | |
| SCHEMBL933688 | 0.76 | PKM (0.45) | CYP19A1CYP3A4CYP2C9CYP2C19KCNA5 | |
| SCHEMBL9372144 | 0.76 | NOTUM (0.46) | CYP19A1CYP3A4CYP2C9CYP2C19MAPT | |
| SCHEMBL934753 | 0.76 | CYP19A1 (0.41) | CYP19A1CYP3A4CYP2C9CYP2C19MAPT | |
| SCHEMBL9373572 | 0.74 | CYP3A4 (0.50) | CYP19A1CYP3A4CYP3A5KCNA5 | |
| SCHEMBL9794542 | 0.74 | CYP19A1 (0.48) | CYP19A1CYP3A4CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL442378 | 0.74 | ALDH1A1 (0.35) | CYP3A4CYP2C9CYP2C19ALDH1A1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140357649-A1 | Phenyl(oxy/thio)alkanol Derivatives | BAYER CROPSCIENCE AG (DE) | 2014-12-04 | — | — | US | claimed |
| EP-2451784-A1 | PHENYL(OXY/THIO)ALKANOL DERIVATIVES | Bayer CropScience AG (DE) | 2012-05-16 | — | — | EP | claimed |
| US-20110039865-A1 | Phenyl(oxy/thio)alkanol Derivatives | BAYER CROPSCIENCE AG (DE) | 2011-02-17 | — | — | US | claimed |
| WO-2011003527-A1 | PHENYL(OXY/THIO)ALKANOL DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2011-01-13 | — | — | WO | claimed |
| US-9321732-B2 | Phenyl(oxy/thio)alkanol derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-04-26 | — | — | US | disclosed |
| US-9051277-B2 | Phenyl(oxy/thio)alkanol derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-06-09 | — | — | US | disclosed |
| US-20140357649-A1 | Phenyl(oxy/thio)alkanol Derivatives | BAYER CROPSCIENCE AG (DE) | 2014-12-04 | — | — | US | disclosed |
| EP-2451784-A1 | PHENYL(OXY/THIO)ALKANOL DERIVATIVES | Bayer CropScience AG (DE) | 2012-05-16 | — | — | EP | disclosed |
| US-20110039865-A1 | Phenyl(oxy/thio)alkanol Derivatives | BAYER CROPSCIENCE AG (DE) | 2011-02-17 | — | — | US | disclosed |
| WO-2011003527-A1 | PHENYL(OXY/THIO)ALKANOL DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2011-01-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140357649-A1 | Phenyl(oxy/thio)alkanol Derivatives | MYB, ALKBH3, OSBP | CYP19A1 1895/4885CYP3A4 1208/4885CYP2C9 3018/4885 |
| US-20110039865-A1 | Phenyl(oxy/thio)alkanol Derivatives | MYB, ALKBH3, OSBP | CYP19A1 1895/4885CYP3A4 1208/4885CYP2C9 3018/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.