Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | GLA | P06280 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | DHODH | Q02127 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CASP1 | P29466 | 2/20 | 0.46 |
| ▸ | CASP7 | P55210 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29377848 | 0.84 | PDE10A (0.66) | HSD17B10PDE10AKDM4EALDH1A1GLA | |
| SCHEMBL641899 | 0.84 | PDE10A (0.66) | HSD17B10PDE10AKDM4EALDH1A1GLA | |
| SCHEMBL17154426 | 0.82 | MDM4 (0.50) | HSD17B10PDE10AKDM4EALDH1A1GLA | |
| Water SCHEMBL2991911 | 0.82 | PDE10A (0.63) | HSD17B10PDE10AKDM4EALDH1A1GLA | |
| Hydrochloric Acid SCHEMBL1603404 | 0.82 | PDE10A (0.63) | HSD17B10PDE10AKDM4EALDH1A1GLA | |
| Iodide SCHEMBL8029606 | 0.82 | PDE10A (0.63) | HSD17B10PDE10AKDM4EALDH1A1GLA | |
| Iodide SCHEMBL8029601 | 0.82 | PDE10A (0.63) | HSD17B10PDE10AKDM4EALDH1A1GLA | |
| Hydrochloric Acid SCHEMBL9597551 | 0.82 | PDE10A (0.63) | HSD17B10PDE10AKDM4EALDH1A1GLA | |
| SCHEMBL3899416 | 0.81 | DHODH (0.55) | HSD17B10PDE10AKDM4EALDH1A1GLA | |
| SCHEMBL7698336 | 0.80 | DHODH (0.59) | HSD17B10KDM4EALDH1A1GLAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0369344-B1 | N-arylation of isatins | ABBOTT LAB (US) | 1994-04-06 | — | — | EP | disclosed |
| EP-0369344-A1 | N-arylation of isatins | ABBOTT LABORATORIES (US) | 1990-05-23 | — | — | EP | disclosed |