Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9330939 | 1.00 | MAPT (0.56) | MAPTALDH1A1KDM4EHSD17B10MEN1 | |
| SCHEMBL9331089 | 0.87 | ALDH1A1 (0.51) | MAPTALDH1A1KDM4EHSD17B10MEN1 | |
| SCHEMBL9330426 | 0.87 | ALDH1A1 (0.51) | MAPTALDH1A1KDM4EHSD17B10MEN1 | |
| SCHEMBL9330750 | 0.86 | MAPT (0.44) | MAPTALDH1A1KMT2ALMNATP53 | |
| SCHEMBL9330756 | 0.86 | MAPT (0.44) | MAPTALDH1A1KMT2ALMNATP53 | |
| SCHEMBL8740665 | 0.81 | MAPT (0.55) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL8937659 | 0.81 | MAPT (0.53) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL31462827 | 0.81 | MAPT (0.50) | MAPTALDH1A1MEN1KMT2ATTR | |
| SCHEMBL8937654 | 0.81 | MAPT (0.53) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9330885 | 0.81 | KDM4E (0.56) | MAPTKDM4EHSD17B10LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376103-B1 | A 2-acylamino-5-halogenated-cinnamic acid derivative and method for its production | NIPPON KAYAKU KK (JP) | 1994-04-20 | — | — | EP | claimed |
| US-4997972-A | 2-acylamino-5-halogenated-cinnamic acid derivative and method for its production | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1991-03-05 | — | — | US | claimed |
| EP-0376103-A1 | A 2-acylamino-5-halogenated-cinnamic acid derivative and method for its production | Nippon Kayaku Kabushiki Kaisha (JP) | 1990-07-04 | — | — | EP | claimed |
| EP-0376103-B1 | A 2-acylamino-5-halogenated-cinnamic acid derivative and method for its production | NIPPON KAYAKU KK (JP) | 1994-04-20 | — | — | EP | disclosed |
| US-4997972-A | 2-acylamino-5-halogenated-cinnamic acid derivative and method for its production | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1991-03-05 | — | — | US | disclosed |
| EP-0376103-A1 | A 2-acylamino-5-halogenated-cinnamic acid derivative and method for its production | Nippon Kayaku Kabushiki Kaisha (JP) | 1990-07-04 | — | — | EP | disclosed |