Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.52 |
| ▸ | ACACB | O00763 | 2/20 | 0.46 |
| ▸ | ACACA | Q13085 | 2/20 | 0.46 |
| ▸ | CETP | P11597 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 3/20 | 0.44 |
| ▸ | PPARA | Q07869 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | CPA1 | P15085 | 1/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9331962 | 0.82 | LTA4H (0.43) | LTA4HFFAR1ACACBACACACNR2 | |
| SCHEMBL9332339 | 0.80 | LTA4H (0.49) | LTA4HFFAR1ACACBACACACNR2 | |
| SCHEMBL8613003 | 0.79 | LTA4H (0.51) | LTA4HFFAR1ACACBACACACETP | |
| SCHEMBL9332001 | 0.79 | LTA4H (0.51) | LTA4HFFAR1ACACBACACACETP | |
| SCHEMBL11354723 | 0.78 | MAPT (0.53) | FFAR1PPARGPPARAFFAR4MME | |
| SCHEMBL9335440 | 0.77 | LTA4H (0.46) | LTA4HFFAR1ACACBACACACNR2 | |
| SCHEMBL10544962 | 0.77 | LTA4H (0.51) | LTA4HFFAR1ACACBACACACETP | |
| Ethane SCHEMBL10958500 | 0.76 | PTGS1 (0.57) | FFAR1PPARGPPARAMMEACE | |
| SCHEMBL3633492 | 0.76 | CETP (0.51) | LTA4HFFAR1CETPPPARGPPARA | |
| SCHEMBL20357561 | 0.75 | FFAR1 (0.57) | LTA4HFFAR1ACACBACACACETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0355800-B1 | Process for the preparation of aryl-dimethyl-3-arylpropyl-silanes | HOECHST AG (DE) | 1994-04-20 | — | — | EP | disclosed |