Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.46 |
| ▸ | CETP | P11597 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | CPA1 | P15085 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | ACACA | Q13085 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9331956 | 0.83 | LTA4H (0.43) | LTA4HLMNAMAPK1L3MBTL1ACACB | |
| SCHEMBL9332336 | 0.80 | LTA4H (0.48) | LTA4HLMNAMAPK1L3MBTL1ACACB | |
| SCHEMBL9332006 | 0.79 | LTA4H (0.53) | LTA4HFFAR1CETPMMEACE | |
| SCHEMBL27491855 | 0.79 | FFAR1 (0.55) | FFAR1MMEACECPA1ACE2 | |
| SCHEMBL9334704 | 0.77 | CASP3 (0.47) | FFAR1SMN1; SMN2TP53RAB9ANPC1 | |
| SCHEMBL6946937 | 0.76 | LTA4H (0.49) | LTA4HFFAR1CETPMMEACE | |
| SCHEMBL10446734 | 0.76 | LTA4H (0.46) | LTA4HFFAR1CETPLMNAMAPK1 | |
| SCHEMBL8613003 | 0.76 | LTA4H (0.51) | LTA4HFFAR1CETPMMEACE | |
| SCHEMBL3633492 | 0.75 | CETP (0.51) | LTA4HFFAR1CETPMMEACE | |
| SCHEMBL5531594 | 0.73 | LTA4H (0.48) | LTA4HFFAR1CETPMMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0355800-B1 | Process for the preparation of aryl-dimethyl-3-arylpropyl-silanes | HOECHST AG (DE) | 1994-04-20 | — | — | EP | disclosed |