Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 8/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.30 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.30 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19956409 | 0.91 | DNM1 (0.48) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL17088153 | 0.91 | DNM1 (0.35) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL703719 | 0.88 | LMNA (0.35) | TSHREPHX1LMNA | |
| SCHEMBL19987907 | 0.86 | — | — | |
| SCHEMBL2596931 | 0.84 | DNM1 (0.31) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL3482185 | 0.83 | LMNA (0.33) | TSHRLMNA | |
| SCHEMBL9120556 | 0.81 | DNM1 (0.43) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL5595779 | 0.79 | DNM1 (0.42) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL3481652 | 0.78 | LMNA (0.33) | TSHRLMNA | |
| SCHEMBL16610527 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0280499-B1 | Novel aminohydrocarbyl-substituted ketoximosilanes | DOW CORNING (US) | 1994-04-13 | — | — | EP | disclosed |
| EP-0280499-A2 | Novel aminohydrocarbyl-substituted ketoximosilanes | DOW CORNING CORPORATION (US) | 1988-08-31 | — | — | EP | disclosed |
| US-4705877-A | Novel aminohydrocarbyl-substituted ketoximosilanes | DOW CORNING CORPORATION (US) | 1987-11-10 | — | — | US | disclosed |