SCHEMBL933253

Cc1cn([C@H]2C[C@H](O)[C@@H]([CH]O[C@@]3(O)C[C@H](n4cc(C)c(=O)[nH]c4=O)O[C@@H]3CO)O2)c(=O)[nH]c1=O

nearest known ligand 0.53

Predicted protein targets (top 2)

	gene	UniProt	supporting neighbours	confidence
▸	TK1	P04183	6/20	0.53

▸	RNASE1	P07998	1/20	0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL8996145	0.82	TK1 (0.51)	TK1
SCHEMBL8356495	0.79	TK1 (0.47)	TK1RNASE1
SCHEMBL65560	0.78	TK1 (0.47)	TK1
SCHEMBL933231	0.78	TK1 (0.47)	TK1
SCHEMBL933229	0.78	TK1 (0.47)	TK1
SCHEMBL932884	0.77	TK1 (0.45)	TK1
SCHEMBL5086587	0.77	LMNA (0.52)	TK1
SCHEMBL6394877	0.77	LMNA (0.52)	TK1
SCHEMBL932666	0.76	TK1 (0.66)	TK1
Phosphoric Acid SCHEMBL4523004	0.76	TK1 (0.48)	TK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-2451461-A1	NOVEL NUCLEIC ACID PRODRUGS AND METHODS OF USE THEREOF	Ontorii, Inc (US)	2012-05-16	—	—	EP	disclosed
WO-2011005761-A1	NOVEL NUCLEIC ACID PRODRUGS AND METHODS USE THEREOF	ONTORII, INC (US)	2011-01-13	—	—	WO	disclosed