Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | CASR | P41180 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.41 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.41 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.41 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL343266 | 0.79 | CASR (0.58) | CYP2C9CYP2C19CASRHDAC3HDAC1 | |
| SCHEMBL5720587 | 0.78 | APEX1 (0.56) | CYP1A2CYP2C9CYP2C19SMN1; SMN2ALDH1A1 | |
| SCHEMBL10429504 | 0.78 | CASR (0.56) | CYP2C9CYP2C19CASRHDAC3HDAC1 | |
| SCHEMBL28785155 | 0.77 | NLRP3 (0.56) | CYP1A2CYP2C9CYP2C19SMN1; SMN2ALDH1A1 | |
| SCHEMBL7825237 | 0.76 | CYP1A2 (0.45) | CYP1A2CYP2C9CYP2C19SMN1; SMN2ALDH1A1 | |
| SCHEMBL11692298 | 0.75 | SMN1; SMN2 (0.52) | CYP1A2CYP2C9CYP2C19SMN1; SMN2CASR | |
| SCHEMBL8591227 | 0.72 | HSD17B10 (0.55) | CYP1A2CYP2C9CYP2C19SMN1; SMN2HDAC3 | |
| SCHEMBL5720482 | 0.72 | CYP1A2 (0.47) | CYP1A2CYP2C9CYP2C19SMN1; SMN2ALDH1A1 | |
| SCHEMBL5720688 | 0.72 | NT5E (0.45) | CYP1A2CYP2C9CYP2C19SMN1; SMN2ALDH1A1 | |
| SCHEMBL10524356 | 0.71 | CISD1 (0.42) | CASRALDH1A1HSD17B10NSD2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9952173-B2 | Lead ion sensors, methods of making and uses thereof | TONGJI UNIVERSITY (CN) | 2018-04-24 | — | — | US | disclosed |
| US-20160231271-A1 | LEAD ION SENSORS, METHODS OF MAKING AND USES THEREOF | TONGJI UNIVERSITY (CN) | 2016-08-11 | — | — | US | disclosed |
| WO-2015042971-A1 | LEAD ION SENSORS, METHODS OF MAKING AND USES THEREOF | TONGJI UNIVERSITY (CN) | 2015-04-02 | — | — | WO | disclosed |
| EP-0402318-B1 | Method of preparing fibre reactive formazane compounds | CIBA GEIGY AG (CH) | 1994-04-20 | — | — | EP | disclosed |
| EP-0402318-A2 | Method of preparing fibre reactive formazane compounds | CIBA-GEIGY AG (CH) | 1990-12-12 | — | — | EP | disclosed |