Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CISD1 | Q9NZ45 | 7/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.41 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NT5E | P21589 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.38 |
| ▸ | CASR | P41180 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14429941 | 0.81 | PRSS1 (0.48) | CISD1GAAPOLBMAPTPKM | |
| SCHEMBL10876157 | 0.77 | APEX1 (0.49) | CISD1NSD2NT5EPOLBMAPT | |
| SCHEMBL11650870 | 0.74 | APEX1 (0.49) | CISD1NSD2CASP6NT5EPOLB | |
| SCHEMBL343266 | 0.72 | CASR (0.58) | NSD2GAAPLCG1DNMT1CASP6 | |
| SCHEMBL9333192 | 0.71 | CYP1A2 (0.47) | NSD2GAAPLCG1DNMT1CASP6 | |
| SCHEMBL10429504 | 0.71 | CASR (0.56) | NSD2GAAPLCG1DNMT1CASP6 | |
| SCHEMBL4649751 | 0.71 | CASP6 (0.62) | NSD2GAAPLCG1DNMT1CASP6 | |
| SCHEMBL9638255 | 0.71 | ADRA2A (0.44) | CISD1GAAALDH1A1HSD17B10GPR84 | |
| SCHEMBL8774997 | 0.70 | CASP6 (0.46) | NSD2GAAPLCG1DNMT1CASP6 | |
| SCHEMBL10878901 | 0.70 | MAPT (0.42) | CISD1NSD2L3MBTL1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4880434-A | FIBER REACTIVE DYES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-11-14 | — | — | US | disclosed |