Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.75 |
| ▸ | NPC1 | O15118 | 6/20 | 0.75 |
| ▸ | RAB9A | P51151 | 6/20 | 0.75 |
| ▸ | TP53 | P04637 | 4/20 | 0.75 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.67 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.67 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.67 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | TNF | P01375 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9332546 | 0.86 | RAB9A (1.00) | SMN1; SMN2NPC1RAB9ATP53POLB | |
| SCHEMBL17776540 | 0.85 | PDPK1 (0.72) | SMN1; SMN2NPC1RAB9APOLBALDH1A1 | |
| SCHEMBL10936004 | 0.84 | DYRK1A (0.75) | SMN1; SMN2NPC1RAB9ATP53POLB | |
| SCHEMBL4405589 | 0.83 | NPC1 (0.63) | SMN1; SMN2NPC1RAB9ATP53POLB | |
| SCHEMBL17251987 | 0.83 | PDPK1 (0.68) | SMN1; SMN2NPC1RAB9APOLBALDH1A1 | |
| SCHEMBL8348837 | 0.83 | PDPK1 (0.68) | SMN1; SMN2NPC1RAB9APOLBALDH1A1 | |
| SCHEMBL30522062 | 0.83 | PDPK1 (0.68) | SMN1; SMN2NPC1RAB9APOLBALDH1A1 | |
| SCHEMBL7933342 | 0.83 | PDPK1 (0.68) | SMN1; SMN2NPC1RAB9APOLBALDH1A1 | |
| SCHEMBL9332424 | 0.81 | SMN1; SMN2 (1.00) | SMN1; SMN2NPC1RAB9ATP53POLB | |
| SCHEMBL9332929 | 0.81 | ALDH1A1 (1.00) | SMN1; SMN2NPC1RAB9ATP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0397169-B1 | Novel benzothiazole derivatives | TOYO BOSEKI (JP) | 1994-04-13 | — | — | EP | claimed |
| US-5036086-A | Novel benzothiazole derivatives | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 1991-07-30 | — | — | US | claimed |
| EP-0397169-A1 | Novel benzothiazole derivatives | TOYO BOSEKI KABUSHIKI KAISHA Trading under the name of Toyobo Co., Ltd. (JP) | 1990-11-14 | — | — | EP | claimed |
| EP-0397169-B1 | Novel benzothiazole derivatives | TOYO BOSEKI (JP) | 1994-04-13 | — | — | EP | disclosed |
| US-5036086-A | Novel benzothiazole derivatives | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 1991-07-30 | — | — | US | disclosed |
| EP-0397169-A1 | Novel benzothiazole derivatives | TOYO BOSEKI KABUSHIKI KAISHA Trading under the name of Toyobo Co., Ltd. (JP) | 1990-11-14 | — | — | EP | disclosed |