Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2846416 | 0.82 | TDP1 (0.55) | CYP3A4TDP1KDM4EGAAESR1 | |
| SCHEMBL9333200 | 0.80 | KDM4E (0.58) | CYP3A4TDP1KDM4EGAAESR1 | |
| SCHEMBL9333180 | 0.80 | KDM4E (0.58) | CYP3A4TDP1KDM4EGAAESR1 | |
| SCHEMBL9333193 | 0.78 | CYP3A4 (0.50) | CYP3A4TDP1KDM4EGAAESR1 | |
| SCHEMBL10819836 | 0.76 | HPGD (0.47) | CYP3A4TDP1KDM4EGAA | |
| SCHEMBL10819832 | 0.75 | KDM4E (0.57) | CYP3A4TDP1KDM4EGAAESR1 | |
| SCHEMBL5028587 | 0.71 | TDP1 (1.00) | CYP3A4TDP1KDM4EGAAESR1 | |
| Benzene SCHEMBL6890099 | 0.71 | TDP1 (1.00) | CYP3A4TDP1KDM4EGAAESR1 | |
| SCHEMBL2085135 | 0.71 | TDP1 (1.00) | CYP3A4TDP1KDM4EGAAESR1 | |
| SCHEMBL101 | 0.71 | TDP1 (1.00) | CYP3A4TDP1KDM4EGAAESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080241589-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | FUJIFILM CORPORATION (JP) | 2008-10-02 | — | — | US | disclosed |
| US-20080241589-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | FUJIFILM CORPORATION (JP) | 2008-10-02 | — | — | US | disclosed |
| EP-0499329-B1 | Carbonylation catalyst system | SHELL INT RESEARCH (NL) | 1994-05-04 | — | — | EP | disclosed |
| US-5189003-A | Of group 8 metal or compound and a polyphosphine | SHELL OIL COMPANY (US) | 1993-02-23 | — | — | US | disclosed |
| EP-0499329-A1 | Carbonylation catalyst system | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1992-08-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080241589-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | OR10J3, AOC2, L1CAM | CYP3A4 522/4885TDP1 2687/4885KDM4E 2429/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.