Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9333361 | 1.00 | KMT2A (0.58) | KMT2AALDH1A1TSHRSMN1; SMN2LMNA | |
| SCHEMBL9336092 | 0.85 | ALDH1A1 (0.56) | KMT2AALDH1A1TSHRSMN1; SMN2LMNA | |
| SCHEMBL9336087 | 0.85 | ALDH1A1 (0.56) | KMT2AALDH1A1TSHRSMN1; SMN2LMNA | |
| SCHEMBL9333403 | 0.82 | PPARG (0.39) | KMT2AALDH1A1TSHRSMN1; SMN2LMNA | |
| SCHEMBL9333392 | 0.82 | PPARG (0.39) | KMT2AALDH1A1TSHRSMN1; SMN2LMNA | |
| SCHEMBL9493004 | 0.80 | KMT2A (0.55) | KMT2AALDH1A1TSHRSMN1; SMN2LMNA | |
| SCHEMBL9493005 | 0.80 | KMT2A (0.55) | KMT2AALDH1A1TSHRSMN1; SMN2LMNA | |
| SCHEMBL9336203 | 0.79 | KMT2A (0.38) | KMT2AALDH1A1TSHRSMN1; SMN2LMNA | |
| SCHEMBL9336192 | 0.79 | KMT2A (0.38) | KMT2AALDH1A1TSHRSMN1; SMN2LMNA | |
| SCHEMBL8637704 | 0.79 | KMT2A (0.53) | KMT2AALDH1A1SMN1; SMN2LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0594573-A1 | PREPARATION OF PROPENOIC ACID DERIVATIVES | AgrEvo UK Limited (GB) | 1994-05-04 | — | — | EP | disclosed |
| US-5264609-A | Etherification and hydrolysis | SCHERING AGROCHEMICALS LIMITED (GB) | 1993-11-23 | — | — | US | disclosed |
| WO-1991007385-A1 | PREPARATION OF PROPENOIC ACID DERIVATIVES | SCHERING AGROCHEMICALS LIMITED (GB) | 1991-05-30 | — | — | WO | disclosed |