Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL444311 | 0.77 | LDHA (0.36) | LDHA | |
| SCHEMBL28639430 | 0.75 | CNR2 (0.36) | LDHA | |
| SCHEMBL677632 | 0.73 | LDHA (0.37) | LDHA | |
| Caricotamide SCHEMBL6546956 | 0.73 | LDHA (0.37) | LDHA | |
| SCHEMBL28661481 | 0.72 | PTGS1 (0.37) | LDHA | |
| SCHEMBL23010949 | 0.70 | LDHA (0.34) | LDHA | |
| SCHEMBL9334235 | 0.69 | — | — | |
| SCHEMBL2205423 | 0.68 | ADRA1D (0.41) | — | |
| SCHEMBL1274356 | 0.68 | LDHA (0.36) | LDHA | |
| SCHEMBL9334241 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0412699-B1 | Nitrosothiol derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1994-04-27 | — | — | EP | disclosed |
| US-5116861-A | Treatment of Hypertension and Angina Pectoris | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-05-26 | — | — | US | disclosed |
| EP-0412699-A2 | Nitrosothiol derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-02-13 | — | — | EP | disclosed |
| US-4804665-A | NERVOUS SYSTEM DISORDERS; COGNITION ACTIVATORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-02-14 | — | — | US | disclosed |