Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 4/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.34 |
| ▸ | DRD3 | P35462 | 4/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.34 |
| ▸ | DRD2 | P14416 | 3/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | HRH1 | P35367 | 2/20 | 0.34 |
| ▸ | HTR2B | P41595 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL9759619 | 0.94 | KMT2A (0.40) | KMT2ARXFP1HTR1AADRA1ADRD3 | |
| Fumaric Acid SCHEMBL9759629 | 0.94 | KMT2A (0.40) | KMT2ARXFP1HTR1AADRA1ADRD3 | |
| SCHEMBL9332095 | 0.89 | KMT2A (0.45) | KMT2ARXFP1HTR1AADRA1ADRD3 | |
| SCHEMBL9759826 | 0.87 | BCHE (0.40) | KMT2AHTR1AADRA1ADRD3KCNH2 | |
| Fumaric Acid SCHEMBL9758792 | 0.85 | KMT2A (0.41) | KMT2ARXFP1HTR1AADRA1ADRD3 | |
| Fumaric Acid SCHEMBL9758783 | 0.85 | KMT2A (0.41) | KMT2ARXFP1HTR1AADRA1ADRD3 | |
| SCHEMBL9334139 | 0.83 | KMT2A (0.40) | KMT2ARXFP1HTR1AADRA1ADRD3 | |
| SCHEMBL9758879 | 0.83 | HTR1A (0.39) | KMT2AHTR1AADRA1ADRD3KCNH2 | |
| Fumaric Acid SCHEMBL9759336 | 0.83 | BCHE (0.39) | KMT2AHTR1AADRA1ADRD3KCNH2 | |
| Fumaric Acid SCHEMBL9759360 | 0.83 | BCHE (0.39) | KMT2AHTR1AADRA1ADRD3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5321026-A | Antispasmodic agents | RHONE-POULENC RORER S.A. (FR) | 1994-06-14 | — | — | US | disclosed |
| US-4985419-A | Analgesics, Diuretics | RHONE-POULENC SANTE (FR) | 1991-01-15 | — | — | US | disclosed |