Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 8/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 8/20 | 0.39 |
| ▸ | DRD3 | P35462 | 8/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 7/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.39 |
| ▸ | DRD2 | P14416 | 5/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 4/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 4/20 | 0.39 |
| ▸ | HTR2A | P28223 | 4/20 | 0.39 |
| ▸ | HRH1 | P35367 | 4/20 | 0.39 |
| ▸ | HTR2B | P41595 | 4/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.39 |
| ▸ | HTR2C | P28335 | 3/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9331579 | 0.89 | USP2 (0.40) | HTR1AADRA1ADRD3KCNH2CHRM2 | |
| SCHEMBL9331883 | 0.89 | USP2 (0.40) | HTR1AADRA1ADRD3KCNH2CHRM2 | |
| SCHEMBL9759706 | 0.88 | USP2 (0.39) | HTR1AADRA1ADRD3KCNH2CHRM2 | |
| SCHEMBL9332048 | 0.88 | USP2 (0.39) | HTR1AADRA1ADRD3KCNH2CHRM2 | |
| SCHEMBL9331978 | 0.88 | USP2 (0.39) | HTR1AADRA1ADRD3KCNH2CHRM2 | |
| SCHEMBL9331955 | 0.85 | LMNA (0.41) | HTR1AADRA1ADRD3KCNH2CHRM2 | |
| SCHEMBL9331947 | 0.85 | LMNA (0.41) | HTR1AADRA1ADRD3KCNH2CHRM2 | |
| SCHEMBL9759826 | 0.85 | BCHE (0.40) | HTR1AADRA1ADRD3KCNH2CHRM2 | |
| SCHEMBL9334129 | 0.83 | KMT2A (0.40) | HTR1AADRA1ADRD3KCNH2CHRM2 | |
| Hydrochloric Acid SCHEMBL9759364 | 0.83 | HTR1A (0.37) | HTR1AADRA1ADRD3KCNH2CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985419-A | Analgesics, Diuretics | RHONE-POULENC SANTE (FR) | 1991-01-15 | — | — | US | disclosed |