Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1F | P30939 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 4/20 | 0.53 |
| ▸ | HTR1B | P28222 | 3/20 | 0.53 |
| ▸ | HTR1D | P28221 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | HTR1E | P28566 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL7765669 | 0.97 | HTR1F (0.53) | HTR1FALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL9333438 | 0.89 | HTR1F (0.68) | HTR1FALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL2360293 | 0.87 | HTR1F (0.52) | HTR1FALDH1A1LMNAKMT2AMEN1 | |
| Oxalic Acid SCHEMBL9334173 | 0.86 | HTR1F (0.64) | HTR1FALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL9263948 | 0.82 | HTR1F (0.52) | HTR1FALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL7743816 | 0.81 | HTR1A (0.60) | ALDH1A1LMNAKMT2AMEN1HTR1A | |
| SCHEMBL9265318 | 0.81 | HTR1A (0.60) | ALDH1A1LMNAKMT2AMEN1HTR1A | |
| SCHEMBL2359786 | 0.81 | HTR1A (0.60) | ALDH1A1LMNAKMT2AMEN1HTR1A | |
| Hydrochloric Acid SCHEMBL9263041 | 0.80 | HTR1A (0.59) | ALDH1A1LMNAKMT2AMEN1HTR1A | |
| SCHEMBL9263920 | 0.80 | HTR1F (0.48) | HTR1FALDH1A1LMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0591280-A1 | USE OF TETRAHYDROCARBAZOLE DERIVATIVES AS 5HT1-RECEPTOR AGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1994-04-13 | — | — | EP | claimed |
| WO-1993000086-A1 | USE OF TETRAHYDROCARBAZONE DERIVATIVES AS 5HT1 RECEPTOR AGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1993-01-07 | — | — | WO | claimed |