Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.34 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 3/20 | 0.33 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | TEC | P42680 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TXK | P42681 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28502339 | 0.71 | POLB (0.48) | MEN1KMT2AKDM4EMAPK1SMN1; SMN2 | |
| SCHEMBL16687023 | 0.69 | DRD2 (0.38) | KDM4ESMN1; SMN2DRD2DRD3 | |
| SCHEMBL20190564 | 0.68 | DRD2 (0.32) | KDM4ESMN1; SMN2DRD2DRD3 | |
| SCHEMBL31648586 | 0.66 | MEN1 (0.60) | MEN1KMT2ACHRNB4CHRNA3KCNH2 | |
| SCHEMBL22720995 | 0.66 | MEN1 (0.60) | MEN1KMT2ACHRNB4CHRNA3KCNH2 | |
| SCHEMBL16610538 | 0.66 | MEN1 (0.73) | MEN1KMT2AHTR2ACHRNB4CHRNA3 | |
| SCHEMBL31648821 | 0.66 | MEN1 (0.60) | MEN1KMT2ACHRNB4CHRNA3KCNH2 | |
| SCHEMBL21055079 | 0.66 | DRD2 (0.34) | MEN1KMT2AMAPK1HTR2AKCNH2 | |
| Hydrochloric Acid SCHEMBL31518158 | 0.66 | MEN1 (0.52) | MEN1KMT2AKDM4EMAPK1CHRNB4 | |
| SCHEMBL27589080 | 0.66 | MEN1 (0.43) | MEN1KMT2AKDM4EMAPK1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0594758-A1 | NOVEL PROCESS FOR AROMATIC BROMINATION | MERCK & CO. INC. (US) | 1994-05-04 | — | — | EP | disclosed |
| WO-1993002036-A1 | NOVEL PROCESS FOR AROMATIC BROMINATION | MERCK & CO., INC. (US) | 1993-02-04 | — | — | WO | disclosed |