⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10361075 | 0.83 | ALDH1A1 (0.31) | — | |
| SCHEMBL11216028 | 0.77 | SMN1; SMN2 (0.38) | — | |
| SCHEMBL11212939 | 0.76 | TSHR (0.31) | — | |
| SCHEMBL9089783 | 0.74 | — | — | |
| SCHEMBL11223421 | 0.72 | TSHR (0.34) | — | |
| SCHEMBL9443375 | 0.70 | MAPT (0.31) | — | |
| SCHEMBL11467922 | 0.67 | — | — | |
| Water SCHEMBL11250631 | 0.67 | — | — | |
| SCHEMBL9600331 | 0.65 | — | — | |
| SCHEMBL9600337 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4547573-A | BACTERICIDES | ICI PHARMA (FR) | 1985-10-15 | — | — | US | claimed |
| US-4504478-A | Cephalosporin-1-oxide derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (FR) | 1985-03-12 | — | — | US | claimed |
| US-4497949-A | PHOTOTHERMOGRAPHY;COLOR FILMS;STORAGE STABILITY;ANTIFOGGING AGENTS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-02-05 | — | — | US | claimed |
| EP-0113965-A2 | Process for the preparation of cephalosporin derivatives | ICI PHARMA (FR) | 1984-07-25 | — | — | EP | claimed |
| EP-0082648-A2 | Cephalosporin derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-06-29 | — | — | EP | claimed |
| EP-0075434-A2 | Cephalosporins, their preparation and their pharmaceutical compositions | ICI PHARMA (FR) | 1983-03-30 | — | — | EP | claimed |
| EP-0072608-A2 | Process for the preparation of cephalosporin derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-02-23 | — | — | EP | claimed |
| EP-0315997-B1 | Cephalosporin compounds and antibacterial agents | MEIJI SEIKA KAISHA (JP) | 1994-04-20 | — | — | EP | disclosed |
| CN-1022629-C | Process for the preparation of novel cephalosporin compounds | MEIJIE SEIKA KAISHA LTD (JP) | 1993-11-03 | — | — | CN | disclosed |
| US-4971961-A | ANTIBIOTICS AS BACTERICIDES AGAINST PSEUDOMONAS | MEIJI SEIKA KAISHA, LTD. (JP) | 1990-11-20 | — | — | US | disclosed |
| EP-0315997-A2 | Cephalosporin compounds and antibacterial agents | MEIJI SEIKA KAISHA LTD. (JP) | 1989-05-17 | — | — | EP | disclosed |
| CN-88102467-A | Process for the preparation of cephalosporin compounds and antibiotics | — | 1988-12-14 | — | — | CN | disclosed |
| US-4758557-A | Cephalosporin derivatives and bactericides containing the same | MEIJI SEIKA KAISHA, LTD. (JP) | 1988-07-19 | — | — | US | disclosed |
| EP-0072608-A2 | Process for the preparation of cephalosporin derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-02-23 | — | — | EP | disclosed |
| US-4329454-A | Cephalosporin compounds | ELI LILLY AND COMPANY (US) | 1982-05-11 | — | — | US | disclosed |
| EP-0002605-B1 | CEPHALOSPORIN COMPOUNDS AND FORMULATIONS CONTAINING THEM FOR USE IN THE TREATMENT OF BACTERIAL INFECTIONS AND THE PREPARATION OF THE CEPHALOSPORIN COMPOUNDS | ELI LILLY AND COMPANY (US) | 1981-12-30 | — | — | EP | disclosed |
| US-4200745-A | 7[2-(2-Aminothiazol-4-yl)-2-alkoxyimino]acetamido 3[4-alkyl-5-oxo-6-hydroxy-3,4 dihydro 1,2,4-triazin 3-yl]thio methyl cephalosporins | ELI LILLY AND COMPANY (US) | 1980-04-29 | — | — | US | disclosed |
| EP-0002605-A1 | Cephalosporin compounds and formulations containing them for use in the treatment of bacterial infections and the preparation of the cephalosporin compounds | ELI LILLY AND COMPANY (US) | 1979-06-27 | — | — | EP | disclosed |
| US-4061861-A | ANTIBIOTIC | ELI LILLY AND COMPANY (US) | 1977-12-06 | — | — | US | disclosed |
| US-4048161-A | ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1977-09-13 | — | — | US | disclosed |