⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9600337 | 0.83 | — | — | |
| SCHEMBL9443375 | 0.71 | MAPT (0.31) | — | |
| Water SCHEMBL11250631 | 0.68 | — | — | |
| SCHEMBL11467922 | 0.68 | — | — | |
| SCHEMBL10361075 | 0.68 | ALDH1A1 (0.31) | — | |
| SCHEMBL9335488 | 0.65 | — | — | |
| SCHEMBL9665495 | 0.65 | — | — | |
| SCHEMBL7306103 | 0.57 | — | — | |
| SCHEMBL28221836 | 0.54 | — | — | |
| SCHEMBL1861019 | 0.49 | MAPT (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0232623-B1 | 1-CARBACEPHALOSPORIN ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1993-03-17 | — | — | EP | disclosed |
| US-4791106-A | 1-Carbacephalosporin antibiotics | ELI LILLY AND COMPANY (US) | 1988-12-13 | — | — | US | disclosed |
| EP-0232623-A1 | 1-Carbacephalosporin antibiotics | ELI LILLY AND COMPANY (US) | 1987-08-19 | — | — | EP | disclosed |