Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | ACE | P12821 | 2/20 | 0.45 |
| ▸ | GHSR | Q92847 | 5/20 | 0.44 |
| ▸ | ECE1 | P42892 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6888466 | 0.93 | USP2 (0.47) | KMT2AMEN1KDM4EALDH1A1CYP3A4 | |
| SCHEMBL8710966 | 0.81 | ACE (0.49) | KMT2AMEN1KDM4EALDH1A1CYP3A4 | |
| SCHEMBL8829880 | 0.80 | ACE (0.50) | KMT2AMEN1KDM4EALDH1A1CYP3A4 | |
| SCHEMBL27330226 | 0.80 | ACE (0.50) | KMT2AMEN1KDM4EALDH1A1CYP3A4 | |
| SCHEMBL9373898 | 0.80 | TACR1 (0.51) | KMT2AMEN1KDM4EALDH1A1CYP3A4 | |
| SCHEMBL9336205 | 0.79 | CYP3A4 (0.42) | KMT2AMEN1KDM4EALDH1A1CYP3A4 | |
| SCHEMBL8700148 | 0.78 | ACE (0.51) | KMT2AMEN1KDM4EALDH1A1CYP3A4 | |
| SCHEMBL8893462 | 0.78 | ACE (0.50) | KMT2AMEN1KDM4EALDH1A1CYP3A4 | |
| SCHEMBL6888854 | 0.77 | TACR1 (0.46) | KMT2AMEN1ACE | |
| SCHEMBL6888621 | 0.76 | TACR1 (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0594692-A1 | CHOLECYSTOKININ ANTAGONISTS USEFUL IN THE TREATMENT OF PANIC ATTACKS | WARNER-LAMBERT COMPANY (US) | 1994-05-04 | — | — | EP | disclosed |