Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | ACE | P12821 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CCKBR | P32239 | 2/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | ECE1 | P42892 | 1/20 | 0.39 |
| ▸ | GHSR | Q92847 | 1/20 | 0.38 |
| ▸ | IL1RN | P18510 | 1/20 | 0.37 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.37 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6888466 | 0.80 | USP2 (0.47) | CYP3A4MAPK1USP2ACEKDM4E | |
| SCHEMBL9336196 | 0.79 | KMT2A (0.47) | CYP3A4MAPK1USP2ACEKDM4E | |
| SCHEMBL8829880 | 0.75 | ACE (0.50) | CYP3A4MAPK1USP2ACEKDM4E | |
| SCHEMBL27330226 | 0.75 | ACE (0.50) | CYP3A4MAPK1USP2ACEKDM4E | |
| SCHEMBL7663984 | 0.74 | CYP3A4 (0.48) | CYP3A4MAPK1USP2ACEKDM4E | |
| SCHEMBL8700148 | 0.73 | ACE (0.51) | CYP3A4MAPK1USP2ACEKDM4E | |
| SCHEMBL8710966 | 0.73 | ACE (0.49) | CYP3A4MAPK1USP2ACEKDM4E | |
| SCHEMBL8893462 | 0.73 | ACE (0.50) | CYP3A4MAPK1USP2ACEKDM4E | |
| SCHEMBL6888621 | 0.71 | TACR1 (0.58) | TACR1 | |
| SCHEMBL8829867 | 0.71 | TACR1 (0.58) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0594692-A1 | CHOLECYSTOKININ ANTAGONISTS USEFUL IN THE TREATMENT OF PANIC ATTACKS | WARNER-LAMBERT COMPANY (US) | 1994-05-04 | — | — | EP | disclosed |