Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RARB | P10826 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28540936 | 1.00 | LMNA (0.39) | LMNAMEN1THRBHTTKMT2A | |
| SCHEMBL8649634 | 1.00 | LMNA (0.39) | LMNAMEN1THRBHTTKMT2A | |
| SCHEMBL2244973 | 1.00 | LMNA (0.39) | LMNAMEN1THRBHTTKMT2A | |
| SCHEMBL2231106 | 1.00 | LMNA (0.39) | LMNAMEN1THRBHTTKMT2A | |
| SCHEMBL1069062 | 1.00 | LMNA (0.39) | LMNAMEN1THRBHTTKMT2A | |
| SCHEMBL17997998 | 1.00 | LMNA (0.39) | LMNAMEN1THRBHTTKMT2A | |
| SCHEMBL2244819 | 1.00 | LMNA (0.39) | LMNAMEN1THRBHTTKMT2A | |
| SCHEMBL2241884 | 1.00 | LMNA (0.39) | LMNAMEN1THRBHTTKMT2A | |
| SCHEMBL7850159 | 1.00 | LMNA (0.39) | LMNAMEN1THRBHTTKMT2A | |
| SCHEMBL4664028 | 0.91 | LMNA (0.39) | LMNAMEN1THRBHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0459705-B1 | Surface-active Organopolysiloxanes | SHINETSU CHEMICAL CO (JP) | 1994-06-01 | — | — | EP | disclosed |
| US-5104998-A | ORGANOPOLYSILOXANE MODIFIED WITH POLYETHER AND HIGHER APLIPHATIC ETHER | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1992-04-14 | — | — | US | disclosed |
| EP-0459705-A2 | Surface-active Organopolysiloxanes | Shin-Etsu Chemical Co., Ltd. (JP) | 1991-12-04 | — | — | EP | disclosed |