Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA3 | P51812 | 5/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 8/20 | 0.44 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.44 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.44 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.44 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.42 |
| ▸ | GCGR | P47871 | 2/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17091623 | 0.85 | CYP11B2 (0.54) | RPS6KA3MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL3719117 | 0.84 | LOXL2 (0.52) | RPS6KA3MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL3820660 | 0.81 | RPS6KA3 (0.44) | RPS6KA3MAPK14SLC22A12GCGRCYP11B1 | |
| SCHEMBL5108906 | 0.81 | GPBAR1 (0.48) | RPS6KA3CYP11B1CYP11B2 | |
| SCHEMBL30944265 | 0.79 | CSNK1D (0.65) | MAPK14MAPK13MAPK12MAPK11GSK3B | |
| SCHEMBL24038370 | 0.76 | RPS6KA3 (0.59) | RPS6KA3MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL27958552 | 0.76 | RPS6KA3 (0.41) | RPS6KA3MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL25126205 | 0.74 | GRM2 (0.44) | RPS6KA3MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL31470912 | 0.73 | RPS6KA3 (0.61) | RPS6KA3MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL23557736 | 0.73 | MAPK14 (0.52) | RPS6KA3MAPK14MAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0300617-B1 | Process for preparing aryl-piperidine carbinols | BEECHAM GROUP PLC (GB) | 1994-05-18 | — | — | EP | disclosed |
| US-5039803-A | Reduction, quaternization; selective production of cis isomer; antidepressants | BEECHAM PHARMACEUTICALS (GB) | 1991-08-13 | — | — | US | disclosed |
| EP-0300617-A1 | Process for preparing aryl-piperidine carbinols | BEECHAM GROUP PLC (GB) | 1989-01-25 | — | — | EP | disclosed |