Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 17/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9336732 | 0.94 | AGTR1 (0.75) | PPARG | |
| SCHEMBL9339366 | 0.94 | PPARG (0.75) | PPARG | |
| SCHEMBL9339152 | 0.93 | PPARG (0.75) | PPARG | |
| SCHEMBL9652474 | 0.90 | PPARG (0.82) | PPARG | |
| SCHEMBL9335484 | 0.90 | PPARG (0.80) | PPARG | |
| SCHEMBL8396598 | 0.90 | AGTR1 (0.79) | PPARG | |
| SCHEMBL9335845 | 0.89 | PPARG (0.79) | PPARG | |
| SCHEMBL9337382 | 0.89 | PPARG (0.79) | PPARG | |
| SCHEMBL9337384 | 0.89 | PPARG (0.79) | PPARG | |
| SCHEMBL9335532 | 0.89 | PPARG (0.79) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0432737-A1 | Cycloheptimidazolone compounds as angiotensin II antagonists for control of hypertension | G.D. Searle & Co. (US) | 1991-06-19 | — | — | EP | claimed |
| US-5281615-A | Hypotensive agents | G. D. SEARLE & CO. (US) | 1994-01-25 | — | — | US | disclosed |
| US-5104891-A | CYCLOHEPTIMIDAZOLONE COMPOUNDS AS ANGIOTENSIN II ANTAGONISTS FOR CONTROL OF HYPERTENSION | G. D. SEARLE & CO. (US) | 1992-04-14 | — | — | US | disclosed |
| EP-0432737-A1 | Cycloheptimidazolone compounds as angiotensin II antagonists for control of hypertension | G.D. Searle & Co. (US) | 1991-06-19 | — | — | EP | disclosed |