Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9337184 | 0.90 | NR4A2 (0.50) | MEN1KMT2ALTA4HMAPK1HRH3 | |
| SCHEMBL9337508 | 0.89 | MAPT (0.57) | MEN1KMT2AMAPK1HRH3ALDH1A1 | |
| SCHEMBL9335613 | 0.86 | LTA4H (0.47) | MEN1KMT2ALTA4HMAPK1HRH3 | |
| SCHEMBL9339374 | 0.83 | NR4A2 (0.51) | MAPK1HRH3ALDH1A1NR4A2L3MBTL1 | |
| SCHEMBL9335769 | 0.81 | NR4A2 (0.51) | MEN1KMT2AMAPK1HRH3ALDH1A1 | |
| SCHEMBL9339404 | 0.81 | TP53 (0.52) | MAPK1HRH3NR4A2HTT | |
| SCHEMBL9335662 | 0.80 | NR4A2 (0.57) | MEN1KMT2ALTA4HALDH1A1NR4A2 | |
| SCHEMBL9339202 | 0.80 | MAPT (0.52) | LTA4HHRH3MAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL9337360 | 0.78 | MAPK1 (0.56) | MEN1KMT2AMAPK1HRH3NR4A2 | |
| SCHEMBL9339336 | 0.78 | NR4A2 (0.48) | MEN1KMT2AMAPK1HRH3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0394440-B1 | PHENYLCARBOXYLIC ACID DERIVATIVES | OTSUKA PHARMA CO LTD (JP) | 1994-05-11 | — | — | EP | disclosed |
| US-4999378-A | Antilipemic, anticholesterol, antidiabetic, treatment of atherosclerosis and obesity | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1991-03-12 | — | — | US | disclosed |
| EP-0394440-A1 | PHENYLCARBOXYLIC ACID DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-10-31 | — | — | EP | disclosed |