Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | RARB | P10826 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ESRRG | P62508 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | RARG | P13631 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9337184 | 0.89 | NR4A2 (0.50) | NR4A2PKMTSHRTP53PLA2G4B | |
| SCHEMBL9335769 | 0.87 | NR4A2 (0.51) | NR4A2PKMTSHRTP53PLA2G4B | |
| SCHEMBL9339404 | 0.87 | TP53 (0.52) | NR4A2PKMTSHRTP53PLA2G4B | |
| SCHEMBL9335662 | 0.86 | NR4A2 (0.57) | NR4A2PKMTSHRTP53PLA2G4B | |
| SCHEMBL9339336 | 0.84 | NR4A2 (0.48) | NR4A2PKMTSHRTP53PLA2G4B | |
| SCHEMBL9337360 | 0.84 | MAPK1 (0.56) | NR4A2PKMTSHRTP53PLA2G4B | |
| SCHEMBL9339424 | 0.84 | ALDH1A1 (0.54) | NR4A2PKMTSHRTP53PLA2G4B | |
| SCHEMBL9337047 | 0.83 | MEN1 (0.51) | NR4A2ALDH1A1L3MBTL1HTTMAPK1 | |
| SCHEMBL9335342 | 0.83 | HTT (0.48) | NR4A2PKMTSHRTP53PLA2G4B | |
| SCHEMBL9335600 | 0.83 | NR4A2 (0.53) | NR4A2PKMPLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0394440-B1 | PHENYLCARBOXYLIC ACID DERIVATIVES | OTSUKA PHARMA CO LTD (JP) | 1994-05-11 | — | — | EP | disclosed |
| US-4999378-A | Antilipemic, anticholesterol, antidiabetic, treatment of atherosclerosis and obesity | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1991-03-12 | — | — | US | disclosed |
| EP-0394440-A1 | PHENYLCARBOXYLIC ACID DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-10-31 | — | — | EP | disclosed |