Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | APEX1 | P27695 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | SNCA | P37840 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | GFER | P55789 | 2/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10690966 | 0.82 | MAPT (0.59) | MAPTRAB9AMEN1KMT2APKM | |
| SCHEMBL31598547 | 0.82 | MEN1 (0.55) | MAPTRAB9AMEN1KMT2ALMNA | |
| SCHEMBL31598552 | 0.82 | ALDH1A1 (0.57) | MAPTRAB9AMEN1KMT2ALMNA | |
| SCHEMBL10718747 | 0.80 | NPC1 (0.58) | MAPTRAB9AMEN1KMT2ATDP1 | |
| SCHEMBL31598565 | 0.80 | CA12 (0.43) | CA12CA1CA2CA9GAA | |
| SCHEMBL10718594 | 0.80 | NPC1 (0.53) | MAPTRAB9AMEN1KMT2ALMNA | |
| SCHEMBL3298240 | 0.80 | RXFP1 (0.62) | MAPTRAB9AMEN1KMT2APKM | |
| SCHEMBL31598537 | 0.80 | ALDH1A1 (0.53) | MAPTRAB9AMEN1KMT2ALMNA | |
| SCHEMBL10717657 | 0.79 | SMN1; SMN2 (0.54) | MAPTRAB9AMEN1KMT2APKM | |
| Hydrochloric Acid SCHEMBL6673965 | 0.78 | RXFP1 (0.61) | MAPTRAB9AMEN1KMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0352222-B1 | Fibre-reactive formazane dyes, process for their preparation and their use | CIBA GEIGY AG (CH) | 1994-05-25 | — | — | EP | disclosed |
| US-5114430-A | Colorfast dyes that react with fibers to form red, orange or red color | CIBA-GEIGY CORPORATION (US) | 1992-05-19 | — | — | US | disclosed |
| US-4994562-A | Colorfast; for dyeing wool, silk | CIBA-GEIGY CORPORATION (US) | 1991-02-19 | — | — | US | disclosed |
| EP-0352222-A2 | Fibre-reactive formazane dyes, process for their preparation and their use | CIBA-GEIGY AG (CH) | 1990-01-24 | — | — | EP | disclosed |