Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 7/20 | 0.39 |
| ▸ | MAOB | P27338 | 7/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | UNG | P13051 | 1/20 | 0.35 |
| ▸ | OGA | O60502 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.35 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
| ▸ | PRKCI | P41743 | 1/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29805500 | 0.81 | MAOA (0.49) | MAOAMAOBNPC1RAB9ATDP1 | |
| SCHEMBL1405364 | 0.81 | MAOA (0.49) | MAOAMAOBNPC1RAB9ATDP1 | |
| Alcohol SCHEMBL9337072 | 0.81 | MAOA (0.43) | MAOAMAOBNPC1RAB9ATDP1 | |
| SCHEMBL4332449 | 0.79 | MAOA (0.47) | MAOAMAOBNPC1RAB9ATDP1 | |
| SCHEMBL30688444 | 0.77 | MAOA (0.39) | MAOAMAOBNPC1RAB9ATDP1 | |
| SCHEMBL3933674 | 0.77 | MAOA (0.39) | MAOAMAOBNPC1RAB9ATDP1 | |
| SCHEMBL30840869 | 0.75 | DUT (0.38) | MAOAMAOBNPC1RAB9ATDP1 | |
| SCHEMBL13439961 | 0.74 | BRD4 (0.41) | MAOAMAOBNPC1RAB9ATDP1 | |
| SCHEMBL1246141 | 0.74 | DUT (0.37) | MAOAMAOBNPC1RAB9ATDP1 | |
| SCHEMBL6525877 | 0.74 | MAOA (0.42) | MAOAMAOBNPC1RAB9ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5322847-A | Inhibit platelet activating factor, block leukotriene D4 receptors | PFIZER INC. (US) | 1994-06-21 | — | — | US | disclosed |