Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 4/20 | 0.59 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.52 |
| ▸ | ACE | P12821 | 1/20 | 0.52 |
| ▸ | FAP | Q12884 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ELANE | P08246 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | REN | P00797 | 1/20 | 0.48 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9337662 | 1.00 | PREP (0.59) | PREPCTRB1ACEFAPKMT2A | |
| SCHEMBL9334682 | 0.93 | PREP (0.60) | PREPCTRB1ACEKMT2AELANE | |
| SCHEMBL9334678 | 0.93 | PREP (0.60) | PREPCTRB1ACEKMT2AELANE | |
| SCHEMBL21632875 | 0.89 | PREP (0.55) | PREPCTRB1ACEFAPKMT2A | |
| SCHEMBL10629309 | 0.89 | PREP (0.55) | PREPCTRB1ACEFAPKMT2A | |
| SCHEMBL21632874 | 0.89 | PREP (0.55) | PREPCTRB1ACEFAPKMT2A | |
| SCHEMBL31742552 | 0.89 | PREP (0.55) | PREPCTRB1ACEFAPKMT2A | |
| SCHEMBL30881918 | 0.87 | PREP (0.53) | PREPCTRB1ACEFAPKMT2A | |
| SCHEMBL27809406 | 0.87 | ACE (0.55) | PREPCTRB1ACEELANEREN | |
| SCHEMBL10954651 | 0.86 | CTRB1 (0.68) | PREPCTRB1KMT2AALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0249434-B1 | Peptide derivatives and processes for their preparation | VYZK USTAV FARM BIOCHEM SP (CZ) | 1994-05-04 | — | — | EP | disclosed |
| US-4898930-A | Peptide derivatives and processes for their preparation | SPOFA, SPOJENE PODNIKY PRO (CS) | 1990-02-06 | — | — | US | disclosed |
| EP-0249434-A2 | Peptide derivatives and processes for their preparation | Vyzkumny ustav pro farmacii a biochemii (CZ) | 1987-12-16 | — | — | EP | disclosed |