Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | TERT | O14746 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9762931 | 0.99 | MAPT (0.44) | MAPTTDP1LMNASMN1; SMN2PPARD | |
| SCHEMBL9341652 | 0.86 | LMNA (0.59) | LMNASMN1; SMN2PPARDKDM4EHDAC3 | |
| SCHEMBL9338093 | 0.86 | LMNA (0.43) | LMNASMN1; SMN2KDM4ELOXL2KMT2A | |
| Hydrochloric Acid SCHEMBL9762697 | 0.85 | LMNA (0.57) | LMNASMN1; SMN2PPARDKDM4EHDAC3 | |
| SCHEMBL9337567 | 0.84 | LMNA (0.49) | LMNASMN1; SMN2KMT2ACA1CA2 | |
| SCHEMBL9337354 | 0.84 | LMNA (0.41) | LMNASMN1; SMN2KDM4EHDAC3LOXL2 | |
| Hydrochloric Acid SCHEMBL9762082 | 0.83 | LMNA (0.48) | LMNASMN1; SMN2KMT2ACA1CA2 | |
| SCHEMBL10634169 | 0.82 | MAPT (0.61) | MAPTTDP1LMNASMN1; SMN2KDM4E | |
| SCHEMBL9619926 | 0.81 | CA2 (0.43) | LMNASMN1; SMN2KDM4EHDAC3LOXL2 | |
| SCHEMBL9337533 | 0.81 | LMNA (0.49) | MAPTTDP1LMNAPPARDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0382111-B1 | Copper complex-formazane compounds, process for their preparation and their use as dyestuffs | HOECHST AG (DE) | 1994-06-08 | — | — | EP | disclosed |
| US-5023325-A | Colorfastness, photostability | CIBA-GEIGY CORPORATION (US) | 1991-06-11 | — | — | US | disclosed |
| US-5015731-A | For fibers such as wool and cellulose | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-05-14 | — | — | US | disclosed |
| US-5003052-A | Monoazo fiber reactive dye for cellulose, polyamides, wool, silk, polyurethanes and leather | CIBA-GEIGY CORPORATION (US) | 1991-03-26 | — | — | US | disclosed |
| US-4786721-A | DYEING OR PRINTING CELLULOSE FIBERS | CIBA-GEIGY CORPORATION (US) | 1988-11-22 | — | — | US | disclosed |
| US-4766206-A | Reactive dyestuffs comprising a vinylsulfonylalkylaminocarbonyl moiety | CIBA-GEIGY CORPORATION (US) | 1988-08-23 | — | — | US | disclosed |