Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 1/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 12/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 10/20 | 0.37 |
| ▸ | THRA | P10827 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9341961 | 0.99 | SLC16A3 (0.41) | SLC16A3LIPGATG4BPLA2G1BTHRA | |
| SCHEMBL9337936 | 0.96 | SLC16A3 (0.38) | SLC16A3LIPGTHRATHRBSMN1; SMN2 | |
| SCHEMBL10497563 | 0.91 | THRA (0.45) | LIPGATG4BPLA2G1BTHRATHRB | |
| SCHEMBL9341673 | 0.91 | SMN1; SMN2 (0.39) | SLC16A3THRBSMN1; SMN2 | |
| SCHEMBL10497772 | 0.89 | THRA (0.45) | ATG4BPLA2G1BTHRATHRBCYP1A2 | |
| SCHEMBL9338280 | 0.86 | SMN1; SMN2 (0.42) | SLC16A3TDP1SMN1; SMN2 | |
| SCHEMBL10497881 | 0.80 | THRA (0.47) | ATG4BPLA2G1BTHRATHRBCYP1A2 | |
| SCHEMBL9338419 | 0.80 | SMN1; SMN2 (0.36) | SLC16A3THRBSMN1; SMN2 | |
| SCHEMBL10497660 | 0.80 | THRA (0.46) | ATG4BPLA2G1BTHRATHRBCYP1A2 | |
| SCHEMBL10585548 | 0.79 | PTGER3 (0.37) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328668-B1 | NONLINEAR OPTICAL MATERIAL | NIPPON OILS & FATS CO LTD (JP) | 1994-05-25 | — | — | EP | disclosed |
| US-5045239-A | Chalcone derivative | NIPPON OIL AND FATS CO., LTD. (JP) | 1991-09-03 | — | — | US | disclosed |
| EP-0328668-A1 | NONLINEAR OPTICAL MATERIAL | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | disclosed |
| EP-0328669-A1 | CHALCONE DERIVATIVE COMPOUNDS | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | disclosed |