Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9341673 | 0.88 | SMN1; SMN2 (0.39) | SMN1; SMN2PTGS1PTGS2HDAC3HDAC4 | |
| SCHEMBL9338323 | 0.85 | SMN1; SMN2 (0.39) | SMN1; SMN2PTGS1PTGS2HDAC3HDAC4 | |
| SCHEMBL9338280 | 0.81 | SMN1; SMN2 (0.42) | SMN1; SMN2PTGS1PTGS2HDAC3HDAC4 | |
| SCHEMBL9337936 | 0.81 | SLC16A3 (0.38) | SMN1; SMN2PTGS1PTGS2HDAC3HDAC4 | |
| SCHEMBL9338260 | 0.80 | SLC16A3 (0.40) | SMN1; SMN2SLC16A3THRB | |
| SCHEMBL9339818 | 0.79 | MAOA (0.38) | SMN1; SMN2PTGS1PTGS2MAOAALDH1A1 | |
| SCHEMBL9339850 | 0.79 | SMN1; SMN2 (0.38) | SMN1; SMN2PTGS1PTGS2MAOAALDH1A1 | |
| SCHEMBL9341961 | 0.79 | SLC16A3 (0.41) | SLC16A3THRB | |
| SCHEMBL10585548 | 0.76 | PTGER3 (0.37) | SMN1; SMN2PTGS1PTGS2NPC1MAPT | |
| SCHEMBL10497772 | 0.76 | THRA (0.45) | KMT2ATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328668-B1 | NONLINEAR OPTICAL MATERIAL | NIPPON OILS & FATS CO LTD (JP) | 1994-05-25 | — | — | EP | disclosed |
| US-5045239-A | Chalcone derivative | NIPPON OIL AND FATS CO., LTD. (JP) | 1991-09-03 | — | — | US | disclosed |
| EP-0328668-A1 | NONLINEAR OPTICAL MATERIAL | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | disclosed |